Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | FRK | P42685 | 2/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.36 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.36 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2650530 | 0.82 | MAP4K4 (0.43) | HSP90AA1EGFRMAPK9MAP4K4FRK | |
| SCHEMBL27798094 | 0.81 | HSP90AA1 (0.42) | HSP90AA1EGFRMAPK9MAP4K4FRK | |
| SCHEMBL5685355 | 0.80 | HSP90AA1 (0.41) | HSP90AA1EGFRMAPK9MAP4K4FRK | |
| SCHEMBL28290775 | 0.79 | EGFR (0.43) | HSP90AA1EGFRMAPK9MAP4K4FRK | |
| SCHEMBL28174574 | 0.78 | MPL (0.42) | HSP90AA1EGFRGSK3B | |
| SCHEMBL27465891 | 0.78 | GRM5 (0.50) | HSP90AA1GSK3BADORA2AADORA2BCDC7 | |
| SCHEMBL27591971 | 0.77 | ALDH1A1 (0.46) | HSP90AA1MAPK9MAPK10MAPK14CCNT1 | |
| SCHEMBL462513 | 0.76 | KDM1A (0.49) | HSP90AA1ADORA2AALDH1A1LMNAMAPT | |
| SCHEMBL16370824 | 0.75 | AAK1 (0.51) | HSP90AA1CLK4CCNT1CCNA2CDK2 | |
| SCHEMBL7089309 | 0.75 | ASIC3 (0.52) | HSP90AA1MAP4K4MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052252-B1 | Diaminobenzene derivatives and dyeing preparations containing them | WELLA AG (DE) | 2003-08-06 | — | — | EP | claimed |
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | claimed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | claimed |
| EP-1052252-B1 | Diaminobenzene derivatives and dyeing preparations containing them | WELLA AG (DE) | 2003-08-06 | — | — | EP | disclosed |
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |