Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088612 | 0.83 | CYP2A6 (0.46) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL7086471 | 0.83 | CYP11B1 (0.43) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL7091233 | 0.83 | IDO1 (0.42) | MEN1MKNK1MKNK2DYRK1BCYP11B1 | |
| SCHEMBL7085699 | 0.83 | CYP11B1 (0.40) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL7088870 | 0.82 | EGFR (0.41) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL7088800 | 0.79 | CYP11B2 (0.41) | CYP11B1CYP11B2DYRK1ACHRNB4CHRNA3 | |
| SCHEMBL7085350 | 0.79 | MAP4K4 (0.45) | CYP11B1CYP11B2IRAK4ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL7133798 | 0.78 | MAP4K4 (0.44) | CYP11B1CYP11B2IRAK4ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL7085454 | 0.78 | MAP4K4 (0.44) | CYP11B1CYP11B2IRAK4ROCK2ROCK1 | |
| SCHEMBL7088853 | 0.78 | ALDH1A1 (0.46) | MEN1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052252-B1 | Diaminobenzene derivatives and dyeing preparations containing them | WELLA AG (DE) | 2003-08-06 | — | — | EP | claimed |
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | claimed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | claimed |
| EP-1052252-B1 | Diaminobenzene derivatives and dyeing preparations containing them | WELLA AG (DE) | 2003-08-06 | — | — | EP | disclosed |
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |