Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL710183 | 0.79 | KDM4E (0.42) | KDM4EALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL707344 | 0.79 | KDM4E (0.42) | KDM4EALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL707319 | 0.77 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL3180184 | 0.74 | CYP11B1 (0.55) | KDM4EALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL4028523 | 0.73 | CYP11B1 (0.54) | KDM4EALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL9823734 | 0.69 | KDM4E (0.69) | KDM4EALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL5146982 | 0.69 | KDM4E (0.69) | KDM4EALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL5332533 | 0.69 | ALDH1A1 (0.62) | KDM4EALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL11483564 | 0.69 | KDM4E (0.62) | KDM4EALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL15452766 | 0.67 | KDM4E (0.74) | KDM4EALDH1A1SMN1; SMN2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118113-B1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA (JP) | 2013-01-30 | — | — | EP | disclosed |
| US-8124760-B2 | Pyridyl-triazolopyrimidine derivative or its salt, pesticide containing it and its production process | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20100087452-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA, LTD (JP) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087452-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | SCN5A, CHRNA5, NR5A2 | KDM4E 1717/4885ALDH1A1 1866/4885SMN1; SMN2 3356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.