Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MBOAT4 | Q96T53 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 4/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL707344 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1MBOAT4NPSR1SMN1; SMN2 | |
| SCHEMBL707319 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1MBOAT4NPSR1SMN1; SMN2 | |
| SCHEMBL708584 | 0.79 | KDM4E (0.64) | KDM4EALDH1A1NPSR1SMN1; SMN2USP2 | |
| SCHEMBL28074599 | 0.70 | TSHR (0.43) | KDM4ENPSR1SMN1; SMN2TSHR | |
| SCHEMBL132252 | 0.66 | GABRA1 (0.46) | KDM4ENPSR1SMN1; SMN2MAPTTSHR | |
| SCHEMBL706407 | 0.66 | TSHR (0.63) | KDM4ENPSR1SMN1; SMN2MAPTTSHR | |
| SCHEMBL30980818 | 0.66 | TSHR (0.63) | KDM4ENPSR1SMN1; SMN2MAPTTSHR | |
| SCHEMBL9632435 | 0.66 | ALDH1A1 (0.43) | KDM4EALDH1A1NPSR1SMN1; SMN2CYP1A2 | |
| SCHEMBL9677374 | 0.66 | ALDH1A1 (0.43) | KDM4EALDH1A1NPSR1SMN1; SMN2CYP1A2 | |
| SCHEMBL29620872 | 0.64 | CYP11B1 (0.46) | KDM4ENPSR1CYP1A2CYP2D6PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118113-B1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA (JP) | 2013-01-30 | — | — | EP | disclosed |
| US-8124760-B2 | Pyridyl-triazolopyrimidine derivative or its salt, pesticide containing it and its production process | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20100087452-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA, LTD (JP) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087452-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | SCN5A, CHRNA5, NR5A2 | KDM4E 1717/4885ALDH1A1 1866/4885MBOAT4 2940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.