Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 1.00 |
| ▸ | ADORA2A | P29274 | 1/20 | 1.00 |
| ▸ | ADORA1 | P30542 | 1/20 | 1.00 |
| ▸ | CHUK | O15111 | 8/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | PRKCG | P05129 | 1/20 | 0.52 |
| ▸ | PRKCB | P05771 | 1/20 | 0.52 |
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | PRKCH | P24723 | 1/20 | 0.52 |
| ▸ | PRKCI | P41743 | 1/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.52 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.52 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.52 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.52 |
| ▸ | KDM5A | P29375 | 4/20 | 0.45 |
| ▸ | IKBKB | O14920 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10486739 | 0.78 | ADORA3 (0.64) | ADORA3ADORA2AADORA1CHUKPRKD3 | |
| SCHEMBL19974114 | 0.77 | ADORA3 (0.62) | ADORA3ADORA2AADORA1CHUKPRKD3 | |
| SCHEMBL7083125 | 0.76 | ADORA3 (0.61) | ADORA3ADORA2AADORA1CHUKPRKD3 | |
| SCHEMBL7082459 | 0.73 | ADORA3 (0.57) | ADORA3ADORA2AADORA1CHUKPRKD3 | |
| SCHEMBL7078407 | 0.73 | ADORA3 (0.57) | ADORA3ADORA2AADORA1CHUKPRKD3 | |
| SCHEMBL31060553 | 0.73 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CHUKPRKD3 | |
| SCHEMBL12396541 | 0.70 | CHUK (0.78) | ADORA3ADORA2AADORA1CHUKPRKD3 | |
| SCHEMBL30322777 | 0.70 | CHUK (0.78) | ADORA3ADORA2AADORA1CHUKPRKD3 | |
| SCHEMBL14330620 | 0.70 | ADORA3 (0.53) | ADORA3ADORA2AADORA1CHUKPRKD3 | |
| SCHEMBL3191588 | 0.69 | CHUK (0.65) | ADORA3ADORA2AADORA1CHUKKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030148259-A1 | Method of identifying insulin secretion stimulating compounds, and the use of such compounds in treating insulin-secretion related disorders | KAROLINSKA INNOVATIONS AB (SE) | 2003-08-07 | — | — | US | claimed |
| WO-2003065036-A1 | METHOD OF IDENTIFYING INSULIN SECRETION STIMULATING COMPOUNDS, AND THE USE OF SUCH COMPOUNDS IN TREATING INSULIN-SECRETION RELATED DISORDERS | KAROLINSKA INNOVATIONS AB (SE) | 2003-08-07 | — | — | WO | claimed |
| JP-1197482-A | — | — | None | — | — | JP | disclosed |
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| US-8551694-B2 | Isolation and use of ryanodine receptors | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-08 | — | — | US | disclosed |
| US-8551694-B2 | Isolation and use of ryanodine receptors | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-08 | — | — | US | disclosed |
| US-20120276554-A1 | ISOLATION AND USE OF RYANODINE RECEPTORS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-01 | — | — | US | disclosed |
| US-20120276554-A1 | ISOLATION AND USE OF RYANODINE RECEPTORS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-01 | — | — | US | disclosed |
| US-8101715-B2 | Ryanodine receptor polypeptides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-24 | — | — | US | disclosed |
| US-8101715-B2 | Ryanodine receptor polypeptides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-24 | — | — | US | disclosed |
| US-7498408-B2 | Ryanodine receptor polypeptides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498408-B2 | Ryanodine receptor polypeptides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-20070161037-A1 | Isolation and use of ryanodine receptors | GUTTERIDGE STEVEN | 2007-07-12 | — | — | US | disclosed |
| US-20070161037-A1 | Isolation and use of ryanodine receptors | GUTTERIDGE STEVEN | 2007-07-12 | — | — | US | disclosed |
| US-20070105098-A1 | Isolation and use of ryanodine receptors | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-05-10 | — | — | US | disclosed |
| US-20070105098-A1 | Isolation and use of ryanodine receptors | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-05-10 | — | — | US | disclosed |
| US-7205147-B2 | Nucleic acids encoding ryanodine receptors | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-04-17 | — | — | US | disclosed |
| US-20030148259-A1 | Method of identifying insulin secretion stimulating compounds, and the use of such compounds in treating insulin-secretion related disorders | KAROLINSKA INNOVATIONS AB (SE) | 2003-08-07 | — | — | US | disclosed |
| JP-H01197482-A | BROMINE-CONTAINING INDOLE | MITSUBISHI KASEI CORP | 1989-08-09 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161037-A1 | Isolation and use of ryanodine receptors | RYR1, RYR2, CHERP | ADORA3 1707/4885ADORA2A 2507/4885ADORA1 2869/4885 |
| US-20120276554-A1 | ISOLATION AND USE OF RYANODINE RECEPTORS | RYR1, RYR2, CACYBP | ADORA3 3058/4885ADORA2A 2997/4885ADORA1 3283/4885 |
| US-20070105098-A1 | Isolation and use of ryanodine receptors | RYR1, RYR2, CHERP | ADORA3 1679/4885ADORA2A 2344/4885ADORA1 2953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.