Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23473 | 0.70 | — | — | |
| SCHEMBL15416348 | 0.68 | ACHE (0.39) | MAOBLMNAALDH1A1HPGDACHE | |
| SCHEMBL1261253 | 0.68 | MAOA (0.35) | FTOMAOAMAOBKDM4E | |
| SCHEMBL28957962 | 0.67 | — | — | |
| SCHEMBL16668859 | 0.66 | — | — | |
| Chromone SCHEMBL29369932 | 0.66 | MAOA (1.00) | FTOMAOAMAOBLMNAMEN1 | |
| Chromone SCHEMBL30075941 | 0.66 | MAOA (1.00) | FTOMAOAMAOBLMNAMEN1 | |
| Chromone SCHEMBL28268880 | 0.66 | MAOA (1.00) | FTOMAOAMAOBLMNAMEN1 | |
| Chromone SCHEMBL37994 | 0.66 | MAOA (1.00) | FTOMAOAMAOBLMNAMEN1 | |
| Chromone SCHEMBL6347379 | 0.66 | MAOA (1.00) | FTOMAOAMAOBLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080934-B1 | (4-OXO-4H-(1)-BENZOPYRAN-8-YL)-ALKANOIC ACIDS, SALTS AND DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1988-01-13 | — | — | EP | claimed |
| EP-1328262-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | Board of Regents, The University of Texas System (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002032413-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-04-25 | — | — | WO | disclosed |