Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.49 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16324307 | 0.88 | FPR2 (0.50) | ALDH1A1LYPLA1LYPLA2MEN1MAPT | |
| SCHEMBL19411422 | 0.87 | ALDH1A1 (0.51) | ALDH1A1LYPLA1LYPLA2NPY2RLMNA | |
| SCHEMBL5112838 | 0.85 | ALDH1A1 (0.74) | ALDH1A1NPY2RLMNAKDM4EMEN1 | |
| SCHEMBL10306736 | 0.80 | CYP2D6 (0.48) | ALDH1A1LMNACHRM3CHRM2CHRM1 | |
| SCHEMBL5490850 | 0.78 | ALDH1A1 (0.65) | ALDH1A1NPY2RLMNAKDM4EMEN1 | |
| SCHEMBL22773254 | 0.77 | ALDH1A1 (0.63) | ALDH1A1NPY2RLMNAKDM4EMEN1 | |
| SCHEMBL21382028 | 0.77 | ALDH1A1 (0.63) | ALDH1A1NPY2RLMNAKDM4EMEN1 | |
| SCHEMBL25339589 | 0.77 | LMNA (0.51) | ALDH1A1LMNACHRM3KEAP1NFE2L2 | |
| SCHEMBL25339600 | 0.77 | LMNA (0.51) | ALDH1A1LMNACHRM3KEAP1NFE2L2 | |
| SCHEMBL25339595 | 0.77 | LMNA (0.51) | ALDH1A1LMNACHRM3KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068807-A2 | ECHINOCANDIN CYCLIC PEPTIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-08-21 | — | — | WO | disclosed |