Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.56 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27937992 | 0.85 | POLB (0.65) | POLBKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL1942279 | 0.82 | POLB (0.71) | POLBKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL1941907 | 0.78 | ALDH1A1 (0.74) | POLBKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL1944863 | 0.76 | RAB9A (0.70) | POLBKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL25246006 | 0.74 | PRKDC (0.71) | KDM4ECSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL1943197 | 0.74 | ALDH1A1 (0.78) | POLBKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7223900 | 0.74 | MAOB (0.61) | POLBALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL29569747 | 0.73 | KDM4E (0.74) | POLBKDM4EUSP2CSNK2A2PTGS1 | |
| Chromocarb SCHEMBL432304 | 0.73 | KDM4E (1.00) | POLBKDM4EUSP2CSNK2A2PTGS1 | |
| Chromocarb SCHEMBL29355904 | 0.73 | KDM4E (1.00) | POLBKDM4EUSP2CSNK2A2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787723-B1 | CYCLOPROPACHROMENECARBOXYLATE DERIVATIVES | SUNTORY LTD (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-5843988-A | Cyclopropachromencarboxylic acid derivatives | SUNTORY LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0787723-A1 | CYCLOPROPACHROMENECARBOXYLATE DERIVATIVES | SUNTORY LIMITED (JP) | 1997-08-06 | — | — | EP | disclosed |