SCHEMBL7086129

SCHEMBL7086129

C=CCOC(=O)C(=C)CC(=O)OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
MAPK1 P28482 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.45
PKM P14618 1/20 0.45
CYP3A4 P08684 1/20 0.44
LMNA P02545 2/20 0.42
TGM2 P21980 1/20 0.42
HCAR2 Q8TDS4 1/20 0.42
SLC6A2 P23975 1/20 0.41
SLC6A3 Q01959 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
CASP1 P29466 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27545595 0.94 SMN1; SMN2 (0.48) ALDH1A1MAPK1L3MBTL1SMN1; SMN2PKM
SCHEMBL1045139 0.88 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1SMN1; SMN2LMNA
SCHEMBL17895893 0.86 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1SMN1; SMN2PKM
SCHEMBL28175313 0.86 ALDH1A1 (0.46) ALDH1A1MAPK1L3MBTL1SMN1; SMN2LMNA
SCHEMBL8397728 0.83 CYP3A4 (0.53) ALDH1A1MAPK1L3MBTL1SMN1; SMN2PKM
SCHEMBL4841728 0.82 ALDH1A1 (0.51) ALDH1A1MAPK1L3MBTL1SMN1; SMN2PKM
SCHEMBL6523916 0.82 ALDH1A1 (0.51) ALDH1A1MAPK1L3MBTL1SMN1; SMN2LMNA
SCHEMBL23704705 0.82 SMN1; SMN2 (0.50) ALDH1A1MAPK1L3MBTL1SMN1; SMN2PKM
SCHEMBL28742954 0.81 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1SMN1; SMN2LMNA
SCHEMBL11064051 0.80 PKM (0.57) ALDH1A1MAPK1L3MBTL1SMN1; SMN2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0242618-B1 Transparent optical article and process for preparing same NIPPON OILS & FATS CO LTD (JP) 1994-11-02 EP claimed
US-4948854-A COPOLYMER INCLUDING ITACONIC ACID DIESTER SEIKO EPSON CORPORATION (JP) 1990-08-14 US claimed
EP-0242618-A2 Transparent optical article and process for preparing same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-10-28 EP claimed
CN-1281975-C Composition for optical material, optical material and plastic lens NOF CORP (JP) 2006-10-25 CN disclosed
CN-1461417-A Composition for optical material, optical material and plastic lens NOF CORP (JP) 2003-12-10 CN disclosed
EP-1331494-A1 COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND PLASTIC LENS NOF CORPORATION (JP) 2003-07-30 EP disclosed
EP-0242618-B1 Transparent optical article and process for preparing same NIPPON OILS & FATS CO LTD (JP) 1994-11-02 EP disclosed
US-4948854-A COPOLYMER INCLUDING ITACONIC ACID DIESTER SEIKO EPSON CORPORATION (JP) 1990-08-14 US disclosed
EP-0242618-A2 Transparent optical article and process for preparing same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-10-28 EP disclosed