Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 13/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | CHAT | P28329 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128126 | 0.81 | RAB9A (0.66) | NFE2L2KDM4ERAB9AAPOBEC3AAPOBEC3G | |
| SCHEMBL16105782 | 0.81 | RAB9A (0.66) | NFE2L2KDM4ERAB9AAPOBEC3AAPOBEC3G | |
| SCHEMBL1128128 | 0.81 | RAB9A (0.66) | NFE2L2KDM4ERAB9AAPOBEC3AAPOBEC3G | |
| SCHEMBL1405665 | 0.80 | NFE2L2 (0.73) | NFE2L2TRPA1RELA | |
| SCHEMBL842427 | 0.80 | NFE2L2 (0.50) | NFE2L2KDM4ERAB9AAPOBEC3AAPOBEC3G | |
| SCHEMBL842428 | 0.80 | NFE2L2 (0.50) | NFE2L2KDM4ERAB9AAPOBEC3AAPOBEC3G | |
| SCHEMBL16959694 | 0.78 | ALDH1A1 (0.37) | NFE2L2KDM4ERAB9AAPOBEC3AAPOBEC3G | |
| SCHEMBL14428487 | 0.78 | ALDH1A1 (0.37) | NFE2L2KDM4ERAB9AAPOBEC3AAPOBEC3G | |
| SCHEMBL135419 | 0.77 | PTGS1 (0.58) | NFE2L2KDM4ERAB9AAPOBEC3AAPOBEC3G | |
| SCHEMBL135418 | 0.77 | PTGS1 (0.58) | NFE2L2KDM4ERAB9AAPOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030113805-A1 | Intrinsically labelled solid support | ZENECA LIMITED, A LONDON CORPORATION | 2003-06-19 | — | — | US | disclosed |
| US-20010007740-A1 | INTRINSICALLY LABELLED SOLID SUPPORT | ZENECA LTD. | 2001-07-12 | — | — | US | disclosed |
| EP-0843656-A1 | INTRINSICALLY LABELLED SOLID SUPPORT | ZENECA LIMITED (GB) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997003931-A1 | INTRINSICALLY LABELLED SOLID SUPPORT | ZENECA LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |