Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962859 | 0.74 | MAPT (0.41) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| Fumaric Acid SCHEMBL7691724 | 0.74 | KDM4E (0.51) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| Fumaric Acid SCHEMBL7086166 | 0.74 | KDM4E (0.51) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL7081070 | 0.72 | TLR8 (0.41) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL7081073 | 0.72 | TLR8 (0.41) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL6963715 | 0.71 | ALDH1A1 (0.50) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL6963711 | 0.71 | ALDH1A1 (0.50) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL5445494 | 0.64 | ALDH1A1 (0.69) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL30162601 | 0.64 | ALDH1A1 (0.69) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL895785 | 0.62 | ALDH1A1 (0.49) | KDM4EALDH1A1GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974584-B1 | FUSED RING COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-6420375-B1 | ANTITUMOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-0974584-A1 | FUSED RING COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-01-26 | — | — | EP | disclosed |