SCHEMBL7086196

SCHEMBL7086196

CCCCCc1cc[nH]c1C=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 2/20 0.45
HIF1A Q16665 1/20 0.44
EPAS1 Q99814 1/20 0.44
LIPG Q9Y5X9 1/20 0.36
TYR P14679 2/20 0.35
MEN1 O00255 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
ALOX5 P09917 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
BID P55957 3/20 0.34
MCL1 Q07820 3/20 0.34
BCL2L1 Q07817 2/20 0.34
BAK1 Q16611 2/20 0.34
KAT8 Q9H7Z6 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28740087 0.98 GPR84 (0.47) GPR84HIF1AEPAS1LIPGTYR
SCHEMBL9225445 0.87 GPR84 (0.33) GPR84HIF1AEPAS1
SCHEMBL6150979 0.82 GPR84 (0.41) GPR84HIF1AEPAS1LIPGTYR
SCHEMBL9625130 0.77 GPR84 (0.47) GPR84TYRMEN1TP53CYP3A4
SCHEMBL28259705 0.76 THRA (0.38) GPR84LIPGTYRMEN1CYP3A4
SCHEMBL31239574 0.76 GPR84 (0.50) GPR84TYRMEN1TP53CYP3A4
SCHEMBL30982563 0.76 GPR84 (0.50) GPR84TYRMEN1TP53CYP3A4
SCHEMBL7613712 0.76 CHEK1 (0.37)
SCHEMBL21645755 0.73 GPR84 (0.46) GPR84HIF1ALIPGTYRMEN1
SCHEMBL82799 0.73 GPR84 (0.46) GPR84HIF1ALIPGTYRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6596935-B2 Chromophores absorb light and exhibit intrinsic molecular level rectification in the flow of excited-state energy and ground-state holes NORTH CAROLINA STATE UNIVERSITY 2003-07-22 US disclosed
EP-1319255-A1 LIGHT HARVESTING ARRAYS NORTH CAROLINA STATE UNIVERSITY (US) 2003-06-18 EP disclosed
US-6559374-B2 Multilayer solar cells NORTH CAROLINA STATE UNIVERSITY 2003-05-06 US disclosed
EP-1303884-A1 SOLAR CELLS INCORPORATING LIGHT HARVESTING ARRAYS NORTH CAROLINA STATE UNIVERSITY (US) 2003-04-23 EP disclosed
US-20020185173-A1 Solar cells incorporating light harvesting arrays NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2002-12-12 US disclosed
US-6420648-B1 SOLAR CELLS NORTH CAROLINA STATE UNIVERSITY 2002-07-16 US disclosed
US-6407330-B1 A CIRCUIT ELECTRICALLY COUPLED TO SAID SOLAR CELL; LIGHT HARVESTING RODS OF NON-DISCOTIC BACKBONE POLYMER CONTAINING CHROMOPHORE GROUPS NORTH CAROLINA STATE UNIVERSITY 2002-06-18 US disclosed
US-20020033192-A1 Trans beta substituted chlorins and methods of making and using the same NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2002-03-21 US disclosed
WO-2002009196-A1 LIGHT HARVESTING ARRAYS NORTH CAROLINA STATE UNIVERSITY (US) 2002-01-31 WO disclosed
WO-2002009197-A1 SOLAR CELLS INCORPORATING LIGHT HARVESTING ARRAYS NORTH CAROLINA STATE UNIVERSITY (US) 2002-01-31 WO disclosed
WO-2002008230-A1 TRANS BETA SUBSTITUTED CHLORINS AND METHODS OF MAKING AND USING THE SAME NORTH CAROLINA STATE UNIVERSITY (US) 2002-01-31 WO disclosed