Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12707407 | 0.89 | PLA2G7 (0.49) | ABL1MAP4K1CASP1TDO2CYP17A1 | |
| SCHEMBL7085997 | 0.86 | CCNC (0.41) | ABL1CASP1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7085966 | 0.85 | GAA (0.43) | CYP17A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL527609 | 0.84 | ABL1 (0.45) | ABL1MAP4K1CASP1TDO2CYP17A1 | |
| SCHEMBL7082047 | 0.83 | PLA2G7 (0.51) | ABL1MAP4K1TDO2CYP17A1CYP1A2 | |
| SCHEMBL7086650 | 0.82 | EP300 (0.44) | CASP1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5687575 | 0.81 | TSHR (0.50) | ABL1MAP4K1CASP1TDO2CYP17A1 | |
| SCHEMBL7085653 | 0.79 | AOC1 (0.39) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL527190 | 0.79 | CYP3A4 (0.48) | ABL1MAP4K1TDO2CYP17A1CYP1A2 | |
| SCHEMBL7085707 | 0.79 | ADRA2B (0.37) | CYP17A1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052252-B1 | Diaminobenzene derivatives and dyeing preparations containing them | WELLA AG (DE) | 2003-08-06 | — | — | EP | claimed |
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | claimed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | claimed |
| EP-1052252-B1 | Diaminobenzene derivatives and dyeing preparations containing them | WELLA AG (DE) | 2003-08-06 | — | — | EP | disclosed |
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |