Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 16/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987223 | 0.78 | IDO1 (0.48) | RORCIDO1FNTAFNTB | |
| SCHEMBL7094552 | 0.78 | IDO1 (0.48) | RORCIDO1FNTAFNTB | |
| SCHEMBL7094305 | 0.70 | IDO1 (0.38) | IDO1FNTAFNTB | |
| SCHEMBL7855700 | 0.69 | IDO1 (0.47) | IDO1FNTAFNTB | |
| SCHEMBL6556871 | 0.68 | IDO1 (0.46) | IDO1FNTAFNTB | |
| SCHEMBL6992643 | 0.68 | CNR1 (0.36) | RORC | |
| SCHEMBL7854078 | 0.68 | IDO1 (0.46) | IDO1FNTAFNTB | |
| SCHEMBL16632803 | 0.68 | RORC (0.59) | RORC | |
| SCHEMBL16633077 | 0.67 | RORC (0.49) | RORC | |
| SCHEMBL7090215 | 0.66 | FNTA (0.48) | RORCIDO1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347966-A1 | FARNESYL TRANSFERASE INHIBITING 4-SUBSTITUTED QUINOLINE AND QUINAZOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002051835-A1 | FARNESYL TRANSFERASE INHIBITING 4-SUBSTITUTED QUINOLINE AND QUINAZOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-07-04 | — | — | WO | disclosed |