Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | FNTA | P49354 | 6/20 | 0.45 |
| ▸ | FNTB | P49356 | 6/20 | 0.45 |
| ▸ | RORC | P51449 | 7/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094552 | 0.91 | IDO1 (0.48) | IDO1FNTAFNTBRORCFABP3 | |
| SCHEMBL7090215 | 0.88 | FNTA (0.48) | IDO1FNTAFNTBRORC | |
| SCHEMBL7094305 | 0.80 | IDO1 (0.38) | IDO1FNTAFNTB | |
| SCHEMBL7855700 | 0.80 | IDO1 (0.47) | IDO1FNTAFNTB | |
| SCHEMBL6556871 | 0.79 | IDO1 (0.46) | IDO1FNTAFNTB | |
| SCHEMBL7854078 | 0.79 | IDO1 (0.46) | IDO1FNTAFNTB | |
| SCHEMBL7086587 | 0.78 | RORC (0.41) | IDO1FNTAFNTBRORC | |
| SCHEMBL7094385 | 0.76 | IDO1 (0.48) | IDO1FNTAFNTBRORCMAPK1 | |
| SCHEMBL7093092 | 0.75 | FNTA (0.44) | IDO1FNTAFNTBRORC | |
| SCHEMBL7217940 | 0.75 | FNTA (0.39) | IDO1FNTAFNTBRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322635-A1 | FARNESYL TRANSFERASE INHIBITING QUINOLINE AND QUINAZOLINE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024682-A1 | FARNESYL TRANSFERASE INHIBITING QUINOLINE AND QUINAZOLINE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-03-28 | — | — | WO | disclosed |