Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SYK | P43405 | 3/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.49 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499712 | 0.93 | SYK (0.52) | SMN1; SMN2MAPTSYKAURKBINCENP | |
| SCHEMBL6490176 | 0.91 | TRPV1 (0.53) | SMN1; SMN2MAPTSMO | |
| SCHEMBL7080851 | 0.89 | SMO (0.49) | SMN1; SMN2MAPTSMOADORA2AADORA1 | |
| SCHEMBL6795959 | 0.88 | MAPT (0.58) | SMN1; SMN2MAPTSMORAB9ANPC1 | |
| SCHEMBL6492508 | 0.88 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTSMOADORA2AADORA1 | |
| SCHEMBL7080737 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTSYKSMORAB9A | |
| Hydrochloric Acid SCHEMBL7079728 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTSMOADORA2AADORA1 | |
| SCHEMBL7085345 | 0.87 | CNR1 (0.55) | SMN1; SMN2MAPTSMOADORA2AADORA1 | |
| SCHEMBL6498179 | 0.86 | RAB9A (0.47) | SMN1; SMN2MAPTSMOADORA2AADORA1 | |
| SCHEMBL6489631 | 0.85 | TAS1R3 (0.56) | SMN1; SMN2MAPTSMOADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |