Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMO | Q99835 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795959 | 0.89 | MAPT (0.58) | SMN1; SMN2MAPTSMORAB9ANPC1 | |
| SCHEMBL6795756 | 0.88 | L3MBTL1 (0.53) | SMN1; SMN2SMORAB9ANPC1HTT | |
| SCHEMBL7086601 | 0.87 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTSMORAB9ANPC1 | |
| SCHEMBL6796673 | 0.87 | HTT (0.59) | MAPTSMORAB9ANPC1HTT | |
| SCHEMBL6795360 | 0.86 | CNR1 (0.50) | SMN1; SMN2MAPTSMORAB9ANPC1 | |
| SCHEMBL6794256 | 0.86 | NPC1 (0.55) | MAPTSMORAB9ANPC1TSHR | |
| SCHEMBL6799491 | 0.86 | TAS1R3 (0.53) | SMN1; SMN2MAPTSMORAB9ANPC1 | |
| SCHEMBL6793890 | 0.85 | RAB9A (0.54) | SMN1; SMN2MAPTSMORAB9ANPC1 | |
| SCHEMBL6795302 | 0.85 | TAS1R3 (0.47) | SMN1; SMN2MAPTSMORAB9ANPC1 | |
| SCHEMBL6791511 | 0.85 | HTT (0.57) | MAPTSMORAB9ANPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |