Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086751 | 0.84 | PTPN11 (0.50) | PTPN11PLAUNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5838346 | 0.81 | NPC1 (0.59) | PTPN11PLAUNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24213305 | 0.81 | NPC1 (0.59) | PTPN11PLAUNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5838349 | 0.81 | NPC1 (0.59) | PTPN11PLAUNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL592655 | 0.77 | PTPN11 (0.59) | PTPN11PLAUNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL592657 | 0.77 | PTPN11 (0.59) | PTPN11PLAUNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7538891 | 0.76 | PLAU (0.46) | PTPN11PLAUNPC1RAB9ASMN1; SMN2 | |
| Nitrophenolate SCHEMBL27457258 | 0.75 | NPC1 (0.59) | PTPN11PLAUNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7538896 | 0.73 | ALDH1A1 (0.40) | PLAUNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9801440 | 0.72 | PLAU (0.56) | PTPN11PLAUNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2134370-A | — | — | None | — | — | JP | disclosed |
| EP-1351944-A1 | METHOD FOR PREPARING 2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE | LG Chem Ltd. (KR) | 2003-10-15 | — | — | EP | disclosed |
| US-6559316-B2 | Reacting o-nitrophenylazohydroxyphenyl compound with hydrazine hydrate; reduction in presence of water, zinc powder, and sulfuric acid with/without phase transfer catalyst | LG CHEM, LTD. (KR) | 2003-05-06 | — | — | US | disclosed |
| US-20030050480-A1 | METHOD FOR PREPARING 2-(2-HYRDROXYPHENYL)-2H-BENZOTRIAZOLE | LG CHEM, LTD. (KR) | 2003-03-13 | — | — | US | disclosed |
| WO-2002055508-A1 | METHOD FOR PREPARING 2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE | LG CHEM, LTD. (KR) | 2002-07-18 | — | — | WO | disclosed |
| US-5571924-A | Process for the preparation of benzotriazoles | CIBA-GEIGY CORPORATION (US) | 1996-11-05 | — | — | US | disclosed |
| US-5276161-A | Catalytic hydrogenation of o-nitrophenylazohydroxyphenyl compounds; noble metal catalyst and organic amine | CIBA-GEIGY CORPORATION (US) | 1994-01-04 | — | — | US | disclosed |
| US-4999433-A | Process for the preparation of benzotriazole derivatives | CIBA-GEIGY CORPORATION (US) | 1991-03-12 | — | — | US | disclosed |
| JP-H02134370-A | PRODUCTION OF BENZOTRIAZOLE DERIVATIVE | CIBA GEIGY AG | 1990-05-23 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030050480-A1 | METHOD FOR PREPARING 2-(2-HYRDROXYPHENYL)-2H-BENZOTRIAZOLE | CYP8B1, CYP4Z1, CBR1 | PTPN11 2902/4885PLAU 3762/4885NPC1 1433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.