SCHEMBL7086753

SCHEMBL7086753

NC(=O)CCC(=O)CCC(N)=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.46
BLM P54132 3/20 0.46
PMP22 Q01453 3/20 0.46
KMT2A Q03164 2/20 0.46
LMNA P02545 4/20 0.41
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
TP53 P04637 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2C19 P33261 2/20 0.41
POLB P06746 2/20 0.41
GMNN O75496 1/20 0.41
USP2 O75604 1/20 0.41
GLA P06280 1/20 0.41
CYP2C9 P11712 1/20 0.41
HPGD P15428 1/20 0.41
THPO P40225 1/20 0.41
RECQL P46063 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinamide SCHEMBL36057 0.88
SCHEMBL30381889 0.85 TDP1 (0.47) ALOX15BLMPMP22KMT2ALMNA
SCHEMBL7771056 0.85 CES2 (0.43) ALOX15BLMPMP22KMT2AALDH1A1
Succinamide SCHEMBL30513314 0.84 LMNA (0.47) ALOX15BLMPMP22KMT2ALMNA
Succinamide SCHEMBL29631488 0.84
Succinamide SCHEMBL28836984 0.84
Succinamide SCHEMBL29269227 0.84
Succinamide SCHEMBL11662331 0.84
Succinamide SCHEMBL21530847 0.84 LMNA (0.47) ALOX15BLMPMP22KMT2ALMNA
Succinamide SCHEMBL1647263 0.84 LMNA (0.47) ALOX15BLMPMP22KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104561616-A Method for producing aluminium alloy ingots from abandoned pop cans DANYANG HENGAN CHEMICAL SCIENCE AND TECHNOLOGY INST CO LTD 2015-04-29 CN claimed
CN-104278156-A Method for reproducing aluminum alloy ingot from waste pop can ZHONGSHAN HONGCHENG RES TECHNICAL SERVICES CO LTD 2015-01-14 CN claimed
CN-118043032-A Topical compositions of 2-phenyl-3, 4-dihydropyrrolo [2, L-F ] [1,2,4] triazinone derivatives and uses thereof 托帕杜制药公司 2024-05-14 CN disclosed
CN-104561616-A Method for producing aluminium alloy ingots from abandoned pop cans DANYANG HENGAN CHEMICAL SCIENCE AND TECHNOLOGY INST CO LTD 2015-04-29 CN disclosed
CN-104278156-A Method for reproducing aluminum alloy ingot from waste pop can ZHONGSHAN HONGCHENG RES TECHNICAL SERVICES CO LTD 2015-01-14 CN disclosed
US-6657069-B2 Reacting 6-aminocarbonylmethyl-4H-2,3- dioxin-4-one compound with alcohol or water to produce 3-oxopentanedicarboxylic acid amide esters; decyclization DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-12-02 US disclosed
US-20030130519-A1 Amido compounds and process for producing the same DAICEL CHEMICAL INDUSTRIES, LTD. 2003-07-10 US disclosed
US-6548674-B2 6-aminocarbonylmethyl-4H-1,3-dioxin-4-ones made by reacting a 6-halomethyl-4H-1,3-dioxin-4-ones with primary or secondary amine and carbon monoxide; intermediate to 3-oxopentanedicarboxylic acid amides for drugs, polyamides DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-04-15 US disclosed
US-20010023297-A1 Amido compounds and process for producing the same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2001-09-20 US disclosed
EP-1132386-A1 Amido compounds and process for producing the same Daicel Chemical Industries, Ltd. (JP) 2001-09-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030130519-A1 Amido compounds and process for producing the same PAM, HAAO, DAO ALOX15 1070/4885BLM 914/4885PMP22 1544/4885
US-20010023297-A1 Amido compounds and process for producing the same PAM, HAAO, DAO ALOX15 1070/4885BLM 914/4885PMP22 1544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.