Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.66 |
| ▸ | BACE1 | P56817 | 1/20 | 0.62 |
| ▸ | KDM5A | P29375 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.54 |
| ▸ | FOS | P01100 | 1/20 | 0.54 |
| ▸ | JUN | P05412 | 1/20 | 0.54 |
| ▸ | EPOR | P19235 | 2/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | TLR4 | O00206 | 1/20 | 0.52 |
| ▸ | TLR2 | O60603 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086903 | 1.00 | ALOX5 (0.66) | ALOX5PTGS1PTGS2BACE1KDM5A | |
| SCHEMBL9380189 | 0.90 | CA12 (0.60) | ALOX5PTGS1PTGS2BACE1KDM5A | |
| SCHEMBL7091399 | 0.90 | P2RX3 (0.57) | ALOX5PTGS1PTGS2BACE1KDM5A | |
| SCHEMBL7091402 | 0.90 | P2RX3 (0.57) | ALOX5PTGS1PTGS2BACE1KDM5A | |
| SCHEMBL9380196 | 0.90 | CA12 (0.60) | ALOX5PTGS1PTGS2BACE1KDM5A | |
| SCHEMBL3290633 | 0.86 | MAOB (0.66) | BCHEMAPTMEN1KMT2ANPC1 | |
| SCHEMBL30970401 | 0.86 | MAOB (0.66) | BCHEMAPTMEN1KMT2ANPC1 | |
| SCHEMBL2774221 | 0.86 | KMT2A (0.65) | BCHEMAPTMEN1KMT2ANPC1 | |
| SCHEMBL31737429 | 0.86 | MAOB (0.66) | BCHEMAPTMEN1KMT2ANPC1 | |
| SCHEMBL3290630 | 0.86 | MAOB (0.66) | BCHEMAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115003704-A | Polymeric composition having excellent storage stability, encapsulating material and display device | 可隆工业株式会社 | 2022-09-02 | — | — | CN | disclosed |
| EP-3145935-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AS DAG-LIPASE INHIBITORS | Universiteit Leiden (NL) | 2017-03-29 | — | — | EP | disclosed |
| WO-2016188972-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AS DAG-LIPASE INHIBITORS | UNIVERSITEIT LEIDEN (NL) | 2016-12-01 | — | — | WO | disclosed |
| EP-3095787-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AS DAG-LIPASE INHIBITORS | Universiteit Leiden (NL) | 2016-11-23 | — | — | EP | disclosed |
| US-20030194375-A1 | Administering 3-aminopropionic acid derivative as anticonvulsant | QUEEN'S UNIVERSITY AT KINGSTON AND NEUROCHEM, INC. | 2003-10-16 | — | — | US | disclosed |
| EP-0363782-B1 | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines | ERBA CARLO SPA (IT) | 1994-01-05 | — | — | EP | disclosed |
| US-5272144-A | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines and pharmaceutical use | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-12-21 | — | — | US | disclosed |
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| EP-0390228-A2 | Chemical intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-03 | — | — | EP | disclosed |
| EP-0363782-A1 | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-04-18 | — | — | EP | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| EP-0240121-A2 | Diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030194375-A1 | Administering 3-aminopropionic acid derivative as anticonvulsant | SLC1A2, SLC1A1, SLC1A3 | ALOX5 314/4885PTGS1 662/4885PTGS2 796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.