Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089437 | 0.84 | LMNA (0.55) | LMNAKDM4EALDH1A1TDP1TSHR | |
| SCHEMBL10385265 | 0.82 | L3MBTL1 (0.64) | LMNAKDM4EALDH1A1TDP1MEN1 | |
| SCHEMBL8164217 | 0.81 | KMT2A (0.56) | LMNAKDM4EALDH1A1TDP1MEN1 | |
| SCHEMBL5319605 | 0.80 | LMNA (0.83) | LMNAALDH1A1TDP1TSHRFFAR4 | |
| SCHEMBL8162827 | 0.80 | LMNA (0.61) | LMNAALDH1A1TSHRFFAR4LTB4R | |
| SCHEMBL8158463 | 0.80 | LMNA (0.61) | LMNAALDH1A1TSHRFFAR4LTB4R | |
| SCHEMBL8149988 | 0.80 | LMNA (0.61) | LMNAALDH1A1TSHRFFAR4LTB4R | |
| SCHEMBL8162521 | 0.80 | LMNA (0.61) | LMNAALDH1A1TSHRFFAR4LTB4R | |
| SCHEMBL8148979 | 0.80 | LMNA (0.61) | LMNAALDH1A1TSHRFFAR4LTB4R | |
| SCHEMBL8164009 | 0.80 | LMNA (0.61) | LMNAALDH1A1TSHRFFAR4LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068806-A1 | SOLID PHASE PEPTIDE SYNTHESIS ON SILICA | JOHNSON MATTHEY PLC (GB) | 2003-08-21 | — | — | WO | claimed |
| WO-2003068806-A1 | SOLID PHASE PEPTIDE SYNTHESIS ON SILICA | JOHNSON MATTHEY PLC (GB) | 2003-08-21 | — | — | WO | disclosed |