Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087897 | 0.86 | CYSLTR2 (0.52) | LMNACYSLTR2CYSLTR1TSHRL3MBTL1 | |
| SCHEMBL22636371 | 0.85 | ATM (0.56) | LMNACYSLTR2CYSLTR1TSHRL3MBTL1 | |
| SCHEMBL29441249 | 0.85 | ATM (0.56) | LMNACYSLTR2CYSLTR1TSHRL3MBTL1 | |
| SCHEMBL7086936 | 0.84 | LMNA (0.55) | LMNACYSLTR2CYSLTR1TSHRMEN1 | |
| SCHEMBL10020554 | 0.82 | L3MBTL1 (0.69) | LMNAL3MBTL1GLAMEN1KMT2A | |
| SCHEMBL4494981 | 0.81 | LMNA (0.63) | LMNACYSLTR2CYSLTR1L3MBTL1GLA | |
| SCHEMBL5319605 | 0.80 | LMNA (0.83) | LMNATSHRL3MBTL1TDP1FFAR4 | |
| SCHEMBL8733422 | 0.80 | CYP1A2 (0.53) | LMNACYSLTR2CYSLTR1L3MBTL1PPARG | |
| SCHEMBL8148979 | 0.80 | LMNA (0.61) | LMNACYSLTR2CYSLTR1TSHRFFAR4 | |
| SCHEMBL8162827 | 0.80 | LMNA (0.61) | LMNACYSLTR2CYSLTR1TSHRFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068806-A1 | SOLID PHASE PEPTIDE SYNTHESIS ON SILICA | JOHNSON MATTHEY PLC (GB) | 2003-08-21 | — | — | WO | claimed |
| WO-2003068806-A1 | SOLID PHASE PEPTIDE SYNTHESIS ON SILICA | JOHNSON MATTHEY PLC (GB) | 2003-08-21 | — | — | WO | disclosed |