SCHEMBL70871

SCHEMBL70871

O=C(Oc1ccccc1)c1ccc(C(=O)Oc2ccccc2)o1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.53
ALOX15 P16050 2/20 0.53
HPGD P15428 1/20 0.53
KMT2A Q03164 6/20 0.53
TSHR P16473 2/20 0.53
ALDH1A1 P00352 2/20 0.53
KDM4E B2RXH2 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MAPT P10636 2/20 0.50
GLA P06280 1/20 0.50
NSD2 O96028 1/20 0.50
F2 P00734 2/20 0.49
NPSR1 Q6W5P4 1/20 0.49
PRSS1 P07477 1/20 0.46
TMPRSS15 P98073 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
MAPK1 P28482 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18913216 0.94 KMT2A (0.49) HSD17B10ALOX15HPGDKMT2ATSHR
SCHEMBL27727679 0.86 KMT2A (0.50) HSD17B10ALOX15HPGDKMT2ATSHR
SCHEMBL1713044 0.86 KMT2A (0.46) HSD17B10ALOX15HPGDKMT2ATSHR
SCHEMBL6829604 0.83 PRSS1 (0.48) HSD17B10ALOX15HPGDKMT2ATSHR
SCHEMBL24262848 0.83 KMT2A (0.54) HSD17B10ALOX15HPGDKMT2ATSHR
SCHEMBL18913218 0.80 KMT2A (0.42) HSD17B10ALOX15HPGDKMT2ATSHR
SCHEMBL17274315 0.77 KMT2A (0.62) HPGDKMT2ATSHRALDH1A1TDP1
SCHEMBL5943067 0.77 KMT2A (0.76) HSD17B10HPGDKMT2ATSHRALDH1A1
SCHEMBL1870544 0.76 PARP10 (0.70) HSD17B10ALOX15HPGDKMT2ATSHR
SCHEMBL70034 0.76 PARP10 (0.70) HSD17B10ALOX15HPGDKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4253370-A2 ORGANOTIN CATALYSTS IN ESTERIFICATION PROCESSES OF FURAN-2,5-DICARBOXYLIC ACID (FDCA) Archer Daniels Midland Company (US) 2023-10-04 EP disclosed
US-11535705-B2 Polycarbonate ester and preparation method therefor SK CHEMICALS CO., LTD. (KR) 2022-12-27 US disclosed
US-20220140252-A1 NOVEL ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-05-05 US disclosed
US-20210171486-A1 ORGANOTIN CATALYSTS IN ESTERIFICATION PROCESSES OF FURAN-2,5-DICARBOXYLIC ACID (FDCA) ARCHER DANIELS MIDLAND COMPANY (US) 2021-06-10 US disclosed
US-10947208-B2 Organotin catalysts in esterification processes of furan-2,5-dicarboxylic acid (FDCA) ARCHER DANIELS MIDLAND COMPANY (US) 2021-03-16 US disclosed
EP-3744750-A1 BIO-BASED POLYCARBONATE ESTER AND PREPARATION METHOD THEREFOR SK Chemicals Co., Ltd. (KR) 2020-12-02 EP disclosed
US-20200362105-A1 BIO-BASED POLYCARBONATE ESTER AND PREPARATION METHOD THEREFOR SK CHEMICALS CO., LTD. (KR) 2020-11-19 US disclosed
US-20200354329-A1 ORGANOTIN CATALYSTS IN ESTERIFICATION PROCESSES OF FURAN-2,5-DICARBOXYLIC ACID (FDCA) ARCHER DANIELS MIDLAND COMPANY (US) 2020-11-12 US disclosed
CN-111630082-A Bio-based polycarbonate and preparation method thereof SK化学公司 2020-09-04 CN disclosed
WO-2018093413-A1 ORGANOTIN CATALYSTS IN ESTERIFICATION PROCESSES OF FURAN-2,5-DICARBOXYLIC ACID (FDCA) ARCHER DANIELS MIDLAND COMPANY (US) 2018-05-24 WO disclosed
WO-2017091437-A1 ORGANOTIN CATALYSTS IN ESTERIFICATION PROCESSES OF FURAN-2,5-DICARBOXYLIC ACID (FDCA) ARCHER DANIELS MIDLAND COMPANY (US) 2017-06-01 WO disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-5549965-A MOLECULAR WEIGHT CONTROLLED BY NON-STOICHIOMETRIC ADDITION OF MONOMER UNITS; ENDS BLOCKED HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-27 US disclosed
US-5422397-A Molding materials, solvent resistance HOECHST AKTIENGESELLSCHAFT (DE) 1995-06-06 US disclosed
US-5393601-A Aromatic polyamide fibers; high strength filters, reinforcing materials HOECHST AKTIENGESELLSCHAFT (DE) 1995-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210171486-A1 ORGANOTIN CATALYSTS IN ESTERIFICATION PROCESSES OF FURAN-2,5-DICARBOXYLIC ACID (FDCA) DERA, FDFT1, OSTC HSD17B10 284/4885ALOX15 3340/4885HPGD 3125/4885
US-20200354329-A1 ORGANOTIN CATALYSTS IN ESTERIFICATION PROCESSES OF FURAN-2,5-DICARBOXYLIC ACID (FDCA) DERA, FDFT1, ADH1C HSD17B10 295/4885ALOX15 3663/4885HPGD 2844/4885
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 HSD17B10 2777/4885ALOX15 1966/4885HPGD 3275/4885
US-20220140252-A1 NOVEL ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LEF1, PIEZO1, L1CAM HSD17B10 2048/4885ALOX15 25/4885HPGD 3044/4885
US-10947208-B2 Organotin catalysts in esterification processes of furan-2,5-dicarboxylic acid (FDCA) DERA, FDFT1, ADH1C HSD17B10 295/4885ALOX15 3663/4885HPGD 2844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.