Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031020 | 0.86 | TAS2R14 (0.36) | TAS2R14ASPHNOTUMAKR1C3AKR1C2 | |
| SCHEMBL20876173 | 0.82 | HTT (0.47) | KDM4EHTT | |
| SCHEMBL3554532 | 0.82 | HTT (0.33) | HTT | |
| SCHEMBL5969078 | 0.82 | HTT (0.33) | NOTUMALDH1A1HTT | |
| SCHEMBL4659254 | 0.82 | SCN9A (0.37) | KDM4EHTT | |
| SCHEMBL13020348 | 0.81 | HTT (0.36) | KDM4EALDH1A1HTT | |
| SCHEMBL3554534 | 0.80 | — | — | |
| SCHEMBL27575241 | 0.80 | KMT2A (0.36) | NOTUMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13064205 | 0.79 | PDK2 (0.33) | KDM4EALDH1A1HTT | |
| SCHEMBL20885320 | 0.79 | BRD4 (0.41) | KDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1360176-B1 | PYRROLECARBOXAMIDES FOR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-11-02 | — | — | EP | claimed |
| EP-1341757-B1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-09-20 | — | — | EP | claimed |
| US-7105565-B2 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | SYNGENTA CROP PROTECTION, INC. (US) | 2006-09-12 | — | — | US | claimed |
| CN-1245384-C | Carboxamides as fungicides in agriculture | SYNGENTA PARTICIPATIONS AG (CH) | 2006-03-15 | — | — | CN | claimed |
| CN-1223584-C | Pyrrolecarboxamides for use as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2005-10-19 | — | — | CN | claimed |
| CN-1221532-C | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | SYNGENTA PARTICIPATIONS AG (CH) | 2005-10-05 | — | — | CN | claimed |
| US-20050119130-A1 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | SYNGENTA CROP PROTECTION, INC. | 2005-06-02 | — | — | US | claimed |
| US-20040171490-A1 | Trifluoromethylpyrrolecarboxamides and Trifluoromethylpyrrolethioamides as fungicides | WALTER HARALD (CH) | 2004-09-02 | — | — | US | claimed |
| US-20040138265-A1 | Carboxamides as fungicides in agriculture | SYNGENTA CROP PROTECTION, INC. | 2004-07-15 | — | — | US | claimed |
| CN-1498208-A | Carboxamides as fungicides in agriculture | �ӳɹ� | 2004-05-19 | — | — | CN | claimed |
| CN-1484637-A | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | �ӳɹ� | 2004-03-24 | — | — | CN | claimed |
| EP-1360176-A1 | PYRROLECARBOXAMIDES FOR USE AS FUNGICIDES | Syngenta Participations AG (CH) | 2003-11-12 | — | — | EP | claimed |
| EP-1355879-A1 | CARBOXAMIDES AS FUNGICIDES IN AGRICULTURE | Syngenta Participations AG (CH) | 2003-10-29 | — | — | EP | claimed |
| EP-1341757-A1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | Syngenta Participations AG (CH) | 2003-09-10 | — | — | EP | claimed |
| CN-1437583-A | Trifluoromethylpyrrole carboxamides and trifluoromethylpyrrolethionamides as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2003-08-20 | — | — | CN | claimed |
| EP-1252139-A1 | TRIFLUOROMETHYLPYRROLE CARBOXAMIDES AND TRIFLUOROMETHYLPYRROLETHIOAMIDES AS FUNGICIDES | Syngenta Participations AG (CH) | 2002-10-30 | — | — | EP | claimed |
| WO-2002064562-A1 | PYRROLECARBOXAMIDES FOR THE USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-08-22 | — | — | WO | claimed |
| WO-2002059086-A1 | CARBOXAMIDES AS FUNGICIDES IN AGRICULTURE | SYNGENTA PARTICIPATIONS AG (CH) | 2002-08-01 | — | — | WO | claimed |
| WO-2002038542-A1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-05-16 | — | — | WO | claimed |
| WO-2001049664-A1 | TRIFLUOROMETHYLPYRROLE CARBOXAMIDES AND TRIFLUOROMETHYLPYRROLETHIOAMIDES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-07-12 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119130-A1 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | CBR3, PYCR1, CBR1 | TAS2R14 1942/4885ASPH 773/4885NOTUM 161/4885 |
| US-20040171490-A1 | Trifluoromethylpyrrolecarboxamides and Trifluoromethylpyrrolethioamides as fungicides | CBR3, CBR1, PYCR1 | TAS2R14 827/4885ASPH 3525/4885NOTUM 407/4885 |
| US-20040138265-A1 | Carboxamides as fungicides in agriculture | CBR3, CBR1, CNPY3 | TAS2R14 765/4885ASPH 1928/4885NOTUM 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.