Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030375 | 0.85 | GLA (0.30) | — | |
| SCHEMBL70872 | 0.82 | TAS2R14 (0.41) | HTT | |
| SCHEMBL20876173 | 0.81 | HTT (0.47) | HTTCES2RAB9ALMNAGAA | |
| SCHEMBL5969078 | 0.81 | HTT (0.33) | HTTCES2RAB9ALMNAGAA | |
| SCHEMBL4659254 | 0.81 | SCN9A (0.37) | HTTCES2RAB9ALMNA | |
| SCHEMBL13020348 | 0.79 | HTT (0.36) | HTTCES2RAB9A | |
| SCHEMBL13064205 | 0.78 | PDK2 (0.33) | HTT | |
| SCHEMBL20885320 | 0.78 | BRD4 (0.41) | HTTRAB9ALMNAGAARECQL | |
| SCHEMBL3554534 | 0.74 | — | — | |
| SCHEMBL13064688 | 0.74 | HTT (0.33) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341757-B1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-09-20 | — | — | EP | claimed |
| US-7105565-B2 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | SYNGENTA CROP PROTECTION, INC. (US) | 2006-09-12 | — | — | US | claimed |
| US-20050119130-A1 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | SYNGENTA CROP PROTECTION, INC. | 2005-06-02 | — | — | US | claimed |
| US-7652059-B2 | 1-methyl-4-trifluoromethyl-1H-pyrrole-3-carboxylic acid [2-(1,3-dimethylbutyl)phenyl]amide; protecting plants against infestation by phytopathogenic microorganisms | SYNGENTA CROP PROTECTION, INC. (US) | 2010-01-26 | — | — | US | disclosed |
| EP-1341757-B1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-09-20 | — | — | EP | disclosed |
| US-7105565-B2 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | SYNGENTA CROP PROTECTION, INC. (US) | 2006-09-12 | — | — | US | disclosed |
| US-20060189676-A1 | Pyrrolcarboxamides and Pyrrolcarbothioamides | SYNGENTA CROP PROTECTION, INC. (US) | 2006-08-24 | — | — | US | disclosed |
| US-20050119130-A1 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | SYNGENTA CROP PROTECTION, INC. | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119130-A1 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | CBR3, PYCR1, CBR1 | HTT 3215/4885CES2 332/4885RAB9A 976/4885 |
| US-20060189676-A1 | Pyrrolcarboxamides and Pyrrolcarbothioamides | CBR3, CTH, PYCR1 | HTT 3153/4885CES2 462/4885RAB9A 1231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.