Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP12 | P39900 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | MMP16 | P51512 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085871 | 0.91 | BRD4 (0.36) | EDNRAELANEACHEAKR1B1TDP1 | |
| SCHEMBL7086242 | 0.84 | MEN1 (0.39) | SMN1; SMN2KDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL7089718 | 0.82 | ALDH1A1 (0.30) | HPGD | |
| SCHEMBL7081707 | 0.81 | AKR1B1 (0.37) | EDNRAAKR1B1TDP1BRD4PTGS2 | |
| SCHEMBL7082800 | 0.79 | AKR1B1 (0.37) | EDNRAAKR1B1TDP1BRD4PTGS2 | |
| SCHEMBL7088888 | 0.79 | EDNRA (0.39) | EDNRAAKR1B1TDP1BRD4PTGS2 | |
| SCHEMBL7088025 | 0.75 | AKR1B1 (0.34) | EDNRAACHEAKR1B1TDP1BRD4 | |
| SCHEMBL7081795 | 0.74 | ADAMTS5 (0.36) | TDP1BRD4PTGS2MEN1KMT2A | |
| SCHEMBL7083197 | 0.71 | MMP2 (0.36) | EDNRAAKR1B1TDP1MMP2MMP12 | |
| SCHEMBL10479325 | 0.69 | GAA (0.40) | EDNRASMN1; SMN2KDM4EMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328262-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | Board of Regents, The University of Texas System (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002032413-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-04-25 | — | — | WO | disclosed |