Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083987 | 0.87 | PDE7A (0.46) | L3MBTL1CYP1A2CYP3A4ALDH1A1KMT2A | |
| SCHEMBL7079695 | 0.82 | MAOA (0.37) | L3MBTL1CYP1A2ALDH1A1KMT2AMEN1 | |
| SCHEMBL7079389 | 0.82 | KMT2A (0.46) | L3MBTL1CYP1A2CYP3A4ALDH1A1KMT2A | |
| SCHEMBL28113250 | 0.75 | LMNA (0.44) | L3MBTL1CYP1A2CYP3A4ALDH1A1KMT2A | |
| SCHEMBL7087536 | 0.74 | L3MBTL1 (0.41) | L3MBTL1CYP1A2CYP3A4ALDH1A1KMT2A | |
| SCHEMBL4033959 | 0.71 | MAPT (0.66) | L3MBTL1CYP1A2CYP3A4ALDH1A1KMT2A | |
| SCHEMBL23863875 | 0.70 | GRIN2D (0.53) | L3MBTL1CYP1A2ALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7084196 | 0.70 | SYK (0.43) | L3MBTL1KMT2ALMNAPOLBNPC1 | |
| SCHEMBL5656690 | 0.69 | L3MBTL1 (0.44) | L3MBTL1CYP1A2CYP3A4ALDH1A1KMT2A | |
| SCHEMBL6187801 | 0.69 | KMT2A (0.51) | L3MBTL1CYP1A2CYP3A4ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |