Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 6/20 | 0.39 |
| ▸ | FNTB | P49356 | 6/20 | 0.39 |
| ▸ | RORC | P51449 | 10/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091329 | 0.91 | IDO1 (0.39) | IDO1FNTAFNTBRORCPGGT1B | |
| SCHEMBL7207240 | 0.89 | TGFBR1 (0.42) | IDO1FNTAFNTBPGGT1B | |
| SCHEMBL7091422 | 0.89 | GAA (0.41) | IDO1FNTAFNTBRORCPGGT1B | |
| SCHEMBL7092843 | 0.81 | FNTA (0.53) | IDO1FNTAFNTBRORCPGGT1B | |
| SCHEMBL5016765 | 0.79 | FNTA (0.46) | IDO1FNTAFNTBPGGT1B | |
| SCHEMBL7205417 | 0.78 | IDO1 (0.43) | IDO1FNTAFNTBPGGT1B | |
| SCHEMBL5655017 | 0.78 | FNTA (0.38) | IDO1FNTAFNTBRORCPGGT1B | |
| SCHEMBL7210392 | 0.74 | IDO1 (0.52) | IDO1FNTAFNTBRORCPGGT1B | |
| SCHEMBL7089905 | 0.73 | IDO1 (0.47) | IDO1FNTAFNTBRORCPGGT1B | |
| SCHEMBL7090215 | 0.73 | FNTA (0.48) | IDO1FNTAFNTBRORCPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322635-A1 | FARNESYL TRANSFERASE INHIBITING QUINOLINE AND QUINAZOLINE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024682-A1 | FARNESYL TRANSFERASE INHIBITING QUINOLINE AND QUINAZOLINE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-03-28 | — | — | WO | disclosed |