Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4125942 | 0.85 | VCAM1 (0.55) | VCAM1ARPELP1KMT2AALDH1A1 | |
| SCHEMBL29625012 | 0.85 | VCAM1 (0.55) | VCAM1ARPELP1KMT2AALDH1A1 | |
| SCHEMBL4433135 | 0.84 | VCAM1 (0.53) | VCAM1ARPELP1KMT2AALDH1A1 | |
| SCHEMBL4446049 | 0.84 | VCAM1 (0.53) | VCAM1ARPELP1KMT2AALDH1A1 | |
| SCHEMBL18394225 | 0.81 | CASP6 (0.64) | LMNA | |
| SCHEMBL18148190 | 0.81 | VCAM1 (0.57) | VCAM1ARPELP1KMT2AALDH1A1 | |
| SCHEMBL5734347 | 0.81 | VCAM1 (0.68) | VCAM1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL31450151 | 0.80 | VCAM1 (0.58) | VCAM1ARPELP1KMT2AALDH1A1 | |
| SCHEMBL18862780 | 0.80 | VCAM1 (0.58) | VCAM1ARPELP1KMT2AALDH1A1 | |
| SCHEMBL2876988 | 0.79 | VCAM1 (0.55) | VCAM1ARPELP1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0878192-B1 | Treating protozoal infections | ALLEGHENY UNIVERSITY OF THE HE (US) | 2003-07-23 | — | — | EP | disclosed |
| US-6500405-B1 | EVALUATING THE SENSITIVITY OF A TEST CELL POPULATION TO AN ANTITUBULIN COMPOUND COMPRISING INCUBATING CELLS OR CELL EXTRACTS WITH AN AMIDE PROBE IN THE PRESENCE AND ABSENCE OF AN ANTITUBULIN TEST COMPOUND | DOW AGROSCIENCES LLC | 2002-12-31 | — | — | US | disclosed |
| EP-0816328-B1 | Process for the manufacture of acetonylbenzamides | DOW AGROSCIENCES LLC (US) | 2002-03-27 | — | — | EP | disclosed |
| US-6140362-A | INHIBITING MAMMALIAN CELL GROWTH IN BENIGN OR MALIGNANT TUMORS COMPRISING TREATING SAID CELLS WITH AN EFFECTIVE AMOUNT OF A N-ACETONYLARYLAMIDES COMPOUND | ROHM AND HAAS COMPANY (US) | 2000-10-31 | — | — | US | disclosed |
| US-6107316-A | USING AN HETEROCYCLIC AMIDE COMPOUND | ROHM AND HAAS COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0843018-B1 | Use of certain amides as probes for detection of antitubulin activity and resistance monitoring | ROHM & HAAS (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-0816331-B1 | Fungicidally active n-acetonylbenzamide compounds | ROHM & HAAS (US) | 2000-05-24 | — | — | EP | disclosed |
| US-5981435-A | APPLYING TO THE LOCUS OF THE ALGAE AN ALGICIDALLY EFFECTIVE AMOUNT OF N-ACETONYLARYLAMIDE DERIVATIVES | ROHM AND HAAS COMPANY (US) | 1999-11-09 | — | — | US | disclosed |
| US-5969200-A | CHLORINATING PARA-TOLUOYL CHLORIDE IN PRESENCE OF CHLORINE GAS AND ALUMINUM CHLORIDE OR ANTIMONY CHLORIDE CATALYST, DISTILLING MIXTURE PRODUCED TO RECOVER 3,5-DICHLORO-4-METHYLBENZOYL CHLORIDE | ROHM AND HAAS COMPANY (US) | 1999-10-19 | — | — | US | disclosed |
| US-5945565-A | SYNTHESIS OF 4-AMINO-3-CHLORO-5-(METHOXYIMINOMETHYL)BENZOYL CHLORIDE STARTING WITH THE CONVERSION OF 5-METHYL-4-NITRO-BENZOIC ACID TO 4-NITRO-5-(METHOXYIMINOMETHYL)-BENZOIC ACID, METHYL ESTER | ROHM AND HAAS COMPANY (US) | 1999-08-31 | — | — | US | disclosed |
| US-5929098-A | Fungicidically active N-acetonylbenzamide compounds | ROHM AND HAAS COMPANY (US) | 1999-07-27 | — | — | US | disclosed |
| US-5874466-A | REACTING AMINE AND ACYL CHLORIDE, HYDROGENOLYSIS | ROHM AND HAAS COMPANY (US) | 1999-02-23 | — | — | US | disclosed |
| EP-0880893-A1 | Method for controlling algae | ROHM AND HAAS COMPANY (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0878192-A2 | Method for treating protozoal infections | Allegheny University of The Health Sciences (US) | 1998-11-18 | — | — | EP | disclosed |
| EP-0843018-A1 | Use of certain amides as probes for detection of antitubulin activity and resistance monitoring | ROHM AND HAAS COMPANY (US) | 1998-05-20 | — | — | EP | disclosed |
| EP-0834311-A1 | Method for inhibiting the growth of mammalian cells | ROHM AND HAAS COMPANY (US) | 1998-04-08 | — | — | EP | disclosed |
| EP-0816331-A1 | Fungicidally active n-acetonylbenzamide compounds | ROHM AND HAAS COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0816328-A2 | Process for the manufacture of acetonylbenzamides | ROHM AND HAAS COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |