SCHEMBL708779

SCHEMBL708779

CCC(C)c1cc(C(C)CC)c(O)c(-n2nc3ccc(OC)cc3n2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.36
RAB9A P51151 6/20 0.36
CRHR1 P34998 2/20 0.36
ALDH1A1 P00352 4/20 0.36
MAPT P10636 3/20 0.36
GAA P10253 2/20 0.36
BCHE P06276 1/20 0.35
TYR P14679 1/20 0.35
ACHE P22303 1/20 0.35
MEN1 O00255 1/20 0.35
PKM P14618 1/20 0.35
KMT2A Q03164 1/20 0.35
HPGD P15428 4/20 0.35
SMN1; SMN2 Q16637 4/20 0.35
LMNA P02545 1/20 0.34
ABCB11 O95342 1/20 0.34
KDM4E B2RXH2 4/20 0.33
HSD17B10 Q99714 3/20 0.33
BACE1 P56817 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29706591 1.00 NPC1 (0.36) NPC1RAB9ACRHR1ALDH1A1MAPT
SCHEMBL11615344 0.87 CA1 (0.36) NPC1RAB9AALDH1A1MAPTGAA
SCHEMBL11416372 0.87 RORC (0.37) NPC1RAB9ACRHR1ALDH1A1MAPT
SCHEMBL8777471 0.84 NPC1 (0.49) NPC1RAB9AALDH1A1MAPTGAA
SCHEMBL709631 0.83 NPC1 (0.41) NPC1RAB9AALDH1A1MAPTGAA
SCHEMBL29438587 0.83 NPC1 (0.41) NPC1RAB9AALDH1A1MAPTGAA
SCHEMBL710416 0.81 RORC (0.40) NPC1RAB9AALDH1A1GAAPKM
SCHEMBL29706550 0.81 RORC (0.40) NPC1RAB9AALDH1A1GAAPKM
SCHEMBL710817 0.80 MAPT (0.34) NPC1RAB9AMAPTGAAHPGD
SCHEMBL29706523 0.80 MAPT (0.34) NPC1RAB9AMAPTGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3758947-B1 HEAT SENSITIVE RECORDING MATERIAL AND COLOR DEVELOPER SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2025-05-14 EP disclosed
US-11512048-B2 Heat sensitive recording material, and color developer SOLENIS TECHNOLOGIES, L.P. (US) 2022-11-29 US disclosed
CN-112601668-B Thermosensitive recording material and color-developing agent 索理思科技开曼公司 2022-07-29 CN disclosed
CN-112601668-A Thermosensitive recording material and color-developing agent 索理思科技开曼公司 2021-04-02 CN disclosed
US-20210002215-A1 HEAT SENSITIVE RECORDING MATERIAL AND COLOR DEVELOPER SOLENIS TECHNOLOGIES CAYMAN, L.P. (KY) 2021-01-07 US disclosed
EP-3533619-A1 HEAT SENSITIVE RECORDING MATERIAL AND COLOR DEVELOPER BASF SE (DE) 2019-09-04 EP disclosed
EP-2794558-B1 HEAT SENSITIVE COATING COMPOSITION BASF SE (DE) 2017-04-26 EP disclosed
US-20140342293-A1 HEAT SENSITIVE COATING COMPOSITION BASF SE (DE) 2014-11-20 US disclosed
US-8247571-B2 Pyridinium and thiazolium conjugates including polyethylene glycols and methods of using the same MYCOSOL, INC. (US) 2012-08-21 US disclosed
US-8124626-B2 Methods of treating inflammations and infections with pyridinium salts MYCOSOL, INC. (US) 2012-02-28 US disclosed
EP-0545442-B1 Microcapsule containing ultraviolet absorber and heat sensitive recording material using the same NEW OJI PAPER CO LTD (JP) 1995-04-05 EP disclosed
US-5272127-A Heat sensitive recording material using microcapsules containing ultraviolet absorber KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-12-21 US disclosed
EP-0545442-A1 Microcapsule containing ultraviolet absorber and heat sensitive recording material using the same NEW OJI PAPER CO., LTD. (JP) 1993-06-09 EP disclosed
US-4522915-A 5-PYRAZOLONE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1985-06-11 US disclosed
US-4407936-A 5-PYRAZOLONE MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1983-10-04 US disclosed
US-4366237-A PYRAZOLONE MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1982-12-28 US disclosed
US-4310619-A LIGHT SENSITIVE ELEMENT COMPRISING A 5-PYRAZOLONE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1982-01-12 US disclosed
US-4308343-A MAGENTA 2-EQUIVALENT COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-12-29 US disclosed
US-4301235-A A PYRAZOLONE MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-11-17 US disclosed
US-4113495-A 2,4,4-TRIMETHYL-2-(2,5-DIHYDROXYPHENYL)-6-HYDROXY-CHROMANS FUJI PHOTO FILM CO., LTD. (JP) 1978-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210002215-A1 HEAT SENSITIVE RECORDING MATERIAL AND COLOR DEVELOPER SCN1A, NCS1, SCN4A NPC1 4413/4885RAB9A 2012/4885CRHR1 2628/4885
US-11512048-B2 Heat sensitive recording material, and color developer SCN1A, NCS1, SCN5A NPC1 4325/4885RAB9A 2153/4885CRHR1 2774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.