Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 5/20 | 0.76 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.76 |
| ▸ | FFAR2 | O15552 | 14/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089044 | 0.94 | OXTR (0.85) | OXTRAVPR1AFFAR2 | |
| SCHEMBL7081248 | 0.94 | OXTR (0.85) | OXTRAVPR1AFFAR2 | |
| SCHEMBL4939000 | 0.94 | OXTR (0.85) | OXTRAVPR1AFFAR2 | |
| SCHEMBL7083601 | 0.92 | OXTR (0.70) | OXTRAVPR1AFFAR2 | |
| SCHEMBL7083269 | 0.92 | OXTR (0.70) | OXTRAVPR1AFFAR2 | |
| SCHEMBL7090234 | 0.92 | OXTR (0.70) | OXTRAVPR1AFFAR2 | |
| SCHEMBL7087086 | 0.91 | OXTR (0.90) | OXTRAVPR1A | |
| SCHEMBL7085545 | 0.86 | OXTR (0.79) | OXTRAVPR1AFFAR2 | |
| SCHEMBL7086784 | 0.86 | OXTR (0.74) | OXTRAVPR1A | |
| SCHEMBL4943198 | 0.86 | OXTR (1.00) | OXTRAVPR1AFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268419-A1 | PYRROLIDINE DERIVATIVES USEFUL AS BAX INHIBITORS | Applied Research Systems ARS Holding N.V. (AN) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001072705-A1 | PHARMACEUTICALLY ACTIVE PYRROLIDINE DERIVATIVES AS BAX INHIBITORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-10-04 | — | — | WO | disclosed |