Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11887458 | 0.81 | TP53 (0.33) | TP53ALDH1A1CYP2C9HPGDALOX15 | |
| SCHEMBL11887457 | 0.81 | TDP1 (0.34) | TP53HPGDALOX15 | |
| SCHEMBL9455519 | 0.80 | PDK2 (0.31) | — | |
| SCHEMBL9688178 | 0.79 | GPR35 (0.32) | — | |
| SCHEMBL9221863 | 0.78 | PDK2 (0.37) | ALDH1A1CYP2C9HPGDALOX15HSD17B10 | |
| SCHEMBL9220858 | 0.77 | PDK2 (0.36) | ALDH1A1CYP2C9HPGDALOX15HSD17B10 | |
| SCHEMBL23045135 | 0.77 | MEN1 (0.31) | — | |
| SCHEMBL1099586 | 0.77 | PDK2 (0.38) | ALDH1A1CYP2C9HPGDALOX15HSD17B10 | |
| SCHEMBL9455467 | 0.75 | PDK2 (0.39) | ALDH1A1 | |
| SCHEMBL15801313 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768559-B1 | Active-matrix liquid crystal displays with polyimide alignment films from 2,2-bis(3,4-dicarboxyphenyl)hexafluoropropane, dianhydride and ortho-substituted aromatic diamines | DU PONT (US) | 2003-08-13 | — | — | EP | claimed |