SCHEMBL1099586

SCHEMBL1099586

O=C(O)c1cc2c(cc1C(=O)O)C(c1ccccc1)(C(F)(F)F)c1cc(C(=O)O)c(C(=O)O)cc1O2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 6/20 0.38
ALOX5 P09917 2/20 0.36
CYP2C9 P11712 1/20 0.36
CDC25A P30304 1/20 0.35
CDC25B P30305 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NOTUM Q6P988 1/20 0.35
ALDH1A1 P00352 2/20 0.33
ALOX15 P16050 1/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
CNR1 P21554 3/20 0.33
GPR35 Q9HC97 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA3 P07451 1/20 0.33
TSHR P16473 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9221863 0.99 PDK2 (0.37) PDK2ALOX5CYP2C9CDC25ACDC25B
SCHEMBL9220858 0.97 PDK2 (0.36) PDK2ALOX5CYP2C9CDC25ACDC25B
SCHEMBL9455620 0.91 PDK2 (0.33) PDK2ALOX5CYP2C9CDC25ACDC25B
SCHEMBL9455626 0.90 CA12 (0.37) PDK2ALOX5CYP2C9GPR35CA12
SCHEMBL9220689 0.89 ALOX5 (0.35) PDK2ALOX5CYP2C9CDC25ACDC25B
SCHEMBL23149786 0.88 ALDH1A1 (0.40) PDK2CDC25ACDC25BHSD17B10NOTUM
SCHEMBL9215677 0.86 KMT2A (0.34) PDK2ALOX5CYP2C9CDC25ACDC25B
SCHEMBL9223896 0.86 ALOX5 (0.33) PDK2ALOX5CYP2C9CDC25ACDC25B
SCHEMBL9223436 0.84 KMT2A (0.33) PDK2ALOX5CYP2C9CDC25ACDC25B
SCHEMBL3274334 0.80 ALOX5 (0.41) ALOX5CYP2C9CDC25ACDC25BHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2092807-B1 COMPOSITE ORGANIC ENCAPSULANTS CDA PROC LTD LIABILITY COMPANY (US) 2013-04-17 EP claimed
US-7745516-B2 Composition of polyimide and sterically-hindered hydrophobic epoxy E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-29 US claimed
US-20090111948-A1 Compositions comprising polyimide and hydrophobic epoxy and phenolic resins, and methods relating thereto CDA PROCESSING LIMITED LIABILITY COMPANY 2009-04-30 US claimed
EP-2027184-A2 HYDROPHOBIC COMPOSITIONS FOR ELECTRONIC APPLICATIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-02-25 EP claimed
US-20080185561-A1 Resistor compositions for electronic circuitry applications U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2008-08-07 US claimed
US-20080185361-A1 Compositions for electronic circuitry applications and methods relating thereto CDA PROCESSING LIMITED LIABILITY COMPANY 2008-08-07 US claimed
EP-1943311-A1 COMPOSITIONS COMPRISING POLYIMIDE AND HYDROPHOBIC EPOXY, AND METHODS RELATING THERETO E.I.Du pont de nemours and company (US) 2008-07-16 EP claimed
WO-2007146382-A2 HYDROPHOBIC COMPOSITIONS FOR ELECTRONIC APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-12-21 WO claimed
US-20070290379-A1 Hydrophobic compositions for electronic applications E. I. DU PONT DE NEMOURS AND COMPANY 2007-12-20 US claimed
WO-2007047384-A1 COMPOSITIONS COMPRISING POLYIMIDE AND HYDROPHOBIC EPOXY, AND METHODS RELATING THERETO E.I. DU PONT DE NEMOURS AND COMPANY (US) 2007-04-26 WO claimed
EP-0758000-B1 Polyimide films from pyromellitic dianhydride and 2,2'-bis(perfluoroalkoxy)benzidines as alignment layers for liquid crystal displays DU PONT (US) 2001-12-19 EP claimed
US-6316170-B2 COATING, EXPOSURE, DEVELOPMENT AND HEAT TREATMENT KABUSHIKI KAISHA TOSHIBA (JP) 2001-11-13 US claimed
US-20010006767-A1 Developing solution and method of forming polyimide pattern by using the developing solution YOSHIAKI KAWAMONZEN 2001-07-05 US claimed
US-5759442-A Polyimide alignment film from 2,2-BIS (3,4-dicarboxyphenyl)--hexafluoropropane dianhydride and ortho-substituted aromatic diamines for active matrix liquid crystal displays E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-06-02 US claimed
US-5731404-A Polyimide film from pyromellitic dianhydride and a bis(4-aminophenoxy) aromatic compound as an alignment layer for liquid crystal displays E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-03-24 US claimed
US-5670609-A FILMS WITH LIQUID CCRYSTAL STRUCTURE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-09-23 US claimed
EP-0772074-A1 Polyimide film from pyromellitic dianhydride and bis(4-aminophenoxy) aromatic compound as an alignment layer for liquid crystal displays E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-05-07 EP claimed
EP-0768559-A1 Polyimide alignment film from 2,2-bis(3,4-dicarboxyphenyl)hexafluoropropane, dianhydride and ortho-substituted aromatic diamines for active matrix liquid crystal displays E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-04-16 EP claimed
EP-0758000-A2 Polyimide films from pyromellitic dianhydride and 2,2'-bis(perfluoroalkoxy)benzidines as alignment layers for liquid crystal displays E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-02-12 EP claimed
US-5399655-A Acid-labile poly(amic acetal ester) E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-03-21 US claimed