SCHEMBL7088090

SCHEMBL7088090

C=C(CC(=O)O)C(=O)OC(C)OCC

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
EGLN1 Q9GZT9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1070832 0.86 LMNA (0.38) LMNA
SCHEMBL9056872 0.83 TSHR (0.33) LMNAALOX15HSD17B10
SCHEMBL3459312 0.83 LMNA (0.42) LMNA
SCHEMBL7988577 0.81 LMNA (0.41) LMNA
SCHEMBL2119109 0.81 ALOX15 (0.35) ALOX15HSD17B10
SCHEMBL7086486 0.81 ALOX15 (0.35) ALOX15HSD17B10EGLN1
SCHEMBL10824306 0.81 ALOX15 (0.38) ALOX15HSD17B10
SCHEMBL8397022 0.81 LMNA (0.44) LMNA
SCHEMBL1521277 0.80 LMNA (0.39) LMNA
SCHEMBL23161023 0.79 LMNA (0.46) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1331494-A1 COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND PLASTIC LENS NOF CORPORATION (JP) 2003-07-30 EP disclosed
US-4463149-A UNSATURATED POLYSILOXANES POLYMER TECHNOLOGY CORPORATION (US) 1984-07-31 US disclosed