Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056862 | 0.88 | LMNA (0.34) | TSHRHPGDALDH1A1LMNA | |
| SCHEMBL7088090 | 0.83 | LMNA (0.38) | LMNAALOX15HSD17B10 | |
| SCHEMBL8398107 | 0.83 | TSHR (0.37) | TSHRHPGDALDH1A1PPARGLMNA | |
| SCHEMBL23161032 | 0.82 | TSHR (0.38) | TSHRHPGDALDH1A1LMNATP53 | |
| SCHEMBL8643739 | 0.80 | PPARG (0.30) | PPARGPPARA | |
| SCHEMBL196351 | 0.80 | TSHR (0.49) | TSHRHPGDALDH1A1LMNA | |
| SCHEMBL2519756 | 0.77 | FAAH (0.34) | ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL2119109 | 0.76 | ALOX15 (0.35) | TSHRALOX15HSD17B10 | |
| SCHEMBL329097 | 0.76 | TSHR (0.52) | TSHRHPGDALDH1A1HCAR2 | |
| SCHEMBL7086486 | 0.76 | ALOX15 (0.35) | TSHRALDH1A1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8277372-A | — | — | None | — | — | JP | disclosed |
| JP-H08277372-A | COATING COMPOSITION | NIPPON OIL & FATS CO LTD | 1996-10-22 | — | — | JP | disclosed |
| US-4463149-A | UNSATURATED POLYSILOXANES | POLYMER TECHNOLOGY CORPORATION (US) | 1984-07-31 | — | — | US | disclosed |