Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7135874 | 0.94 | THRA (0.73) | THRATHRB | |
| SCHEMBL7140230 | 0.90 | THRA (0.53) | THRATHRB | |
| SCHEMBL7133145 | 0.84 | THRA (0.60) | THRATHRB | |
| SCHEMBL7088673 | 0.80 | THRA (1.00) | THRATHRB | |
| SCHEMBL7131020 | 0.79 | THRA (0.58) | THRATHRB | |
| SCHEMBL7138299 | 0.78 | THRA (0.38) | THRATHRB | |
| SCHEMBL7225729 | 0.78 | THRA (0.53) | THRATHRB | |
| SCHEMBL7229224 | 0.78 | THRA (0.53) | THRATHRB | |
| SCHEMBL7223069 | 0.77 | THRA (0.56) | THRATHRB | |
| SCHEMBL7138045 | 0.77 | THRA (0.48) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324987-A1 | INDAZOLES WITH THYROID HORMON LIKE ACTIVITY, A PROCESS FOR ITS PREPARATION AND ITS USE IN PHARMACEUTICAL COMPOSITIONS | Bayer Aktiengesellschaft (DE) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002022586-A1 | INDAZOLES HAVING AN ACTION SIMILAR TO THAT OF A THYROID HORMONE, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE IN MEDICAMENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | WO | disclosed |