Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13084100 | 1.00 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL14441602 | 0.97 | TRIM24 (0.33) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL13563888 | 0.92 | — | — | |
| SCHEMBL3241777 | 0.90 | TRIM24 (0.43) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL2775918 | 0.86 | TRIM24 (0.40) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL25225227 | 0.86 | — | — | |
| SCHEMBL515401 | 0.83 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL515266 | 0.83 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL5740964 | 0.81 | TRIM24 (0.40) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL1700931 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210380606-A1 | 5-AZAINDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2021-12-09 | — | — | US | claimed |
| EP-2983473-A2 | PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF | ALS Mountain Llc (US) | 2016-02-17 | — | — | EP | claimed |
| WO-2014144130-A2 | PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF | ALS MOUNTAIN LLC (US) | 2014-09-18 | — | — | WO | claimed |
| EP-1461339-A2 | SPIROAZACYCLIC COMPOUNDS AS MONOAMINE RECEPTOR MODULATORS | Acadia Pharmaceuticals Inc. (US) | 2004-09-29 | — | — | EP | claimed |
| WO-2003057698-A2 | SPIROAZACYCLIC COMPOUNDS AS MONOAMINE RECEPTOR MODULATORS | ACADIA PHARMACEUTICALS, INC. (US) | 2003-07-17 | — | — | WO | claimed |
| EP-0743312-B1 | Spiroheterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-11-17 | — | — | EP | claimed |
| EP-0743312-A1 | Spiroheterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-11-20 | — | — | EP | claimed |
| EP-4356894-A1 | SUSTAINABLE PRODUCT WITH MALODORS | Beiersdorf AG (DE) | 2024-04-24 | — | — | EP | disclosed |
| US-20230174514-A1 | AZETIDIN-3-YLMETHANOL DERIVATIVES AS CCR6 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-06-08 | — | — | US | disclosed |
| EP-3402784-A1 | 3-((HETERO-)ARYL)-ALKYL-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | Grünenthal GmbH (DE) | 2018-11-21 | — | — | EP | disclosed |
| US-9926319-B2 | Pyridyl piperidines | MERCK PATENT GMBH (DE) | 2018-03-27 | — | — | US | disclosed |
| WO-2017121648-A1 | 3-((HETERO-)ARYL)-ALKYL-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | Grünenthal GmbH (DE) | 2017-07-20 | — | — | WO | disclosed |
| EP-3169665-A1 | SUBSTITUTED AZA-SPIRO(4.5)DECAN-DERIVATIVES | Grünenthal GmbH (DE) | 2017-05-24 | — | — | EP | disclosed |
| EP-1032560-A1 | POSITION-4 SUBSTITUTED 2-PYRROLIDINONE DERIVATIVES TO REDUCE THE LEVEL OF EXTRACELLULAR GLUTAMATE | KLINIKUM DER ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2000-09-06 | — | — | EP | disclosed |
| EP-0743312-B1 | Spiroheterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-11-17 | — | — | EP | disclosed |
| WO-1999025683-A1 | POSITION-4 SUBSTITUTED 2-PYRROLIDINONE DERIVATIVES TO REDUCE THE LEVEL OF EXTRACELLULAR GLUTAMATE | KLINIKUM DER ALBERT-LUDWIGS-UNIVERSITäT FREIBURG (DE) | 1999-05-27 | — | — | WO | disclosed |
| US-5849802-A | Fungicidal spirocyclic amines | AMERICAN CYANAMID COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0743312-A1 | Spiroheterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-11-20 | — | — | EP | disclosed |
| EP-0418190-A2 | Use of 1-oxaspiro[4.4]nonan-2-on as a perfuming agent | Dragoco Gerberding & Co. GmbH (DE) | 1991-03-20 | — | — | EP | disclosed |
| EP-0414275-A2 | Process for the preparation of cyclic aminoacid derivitives as well as the intermediate products | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1991-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210380606-A1 | 5-AZAINDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | ADORA2A, ADORA2B, ADORA1 | TRIM24 4135/4885TRIM33 2730/4885ALDH1A1 343/4885 |
| US-20230174514-A1 | AZETIDIN-3-YLMETHANOL DERIVATIVES AS CCR6 RECEPTOR MODULATORS | CCR6, CCR1, CCR3 | TRIM24 1099/4885TRIM33 1051/4885ALDH1A1 1097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.