Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 12/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089040 | 1.00 | NOTUM (0.40) | NOTUMSMN1; SMN2NPSR1ALDH1A1NPC1 | |
| SCHEMBL7017303 | 0.88 | NPC1 (0.37) | NOTUMSMN1; SMN2NPSR1ALDH1A1NPC1 | |
| SCHEMBL7092396 | 0.88 | NPC1 (0.37) | NOTUMSMN1; SMN2NPSR1ALDH1A1NPC1 | |
| SCHEMBL7093369 | 0.87 | NPC1 (0.37) | NOTUMSMN1; SMN2NPSR1ALDH1A1NPC1 | |
| SCHEMBL7013961 | 0.87 | NPC1 (0.37) | NOTUMSMN1; SMN2NPSR1ALDH1A1NPC1 | |
| SCHEMBL7092603 | 0.84 | NPBWR1 (0.38) | NOTUMSMN1; SMN2NPSR1ALDH1A1NPC1 | |
| SCHEMBL7023491 | 0.84 | NPBWR1 (0.38) | NOTUMSMN1; SMN2NPSR1ALDH1A1NPC1 | |
| SCHEMBL7018209 | 0.83 | ALDH1A1 (0.38) | NOTUMSMN1; SMN2NPSR1ALDH1A1NPC1 | |
| SCHEMBL7093687 | 0.83 | ALDH1A1 (0.38) | NOTUMSMN1; SMN2NPSR1ALDH1A1NPC1 | |
| SCHEMBL7094438 | 0.80 | NPBWR1 (0.35) | NOTUMSMN1; SMN2NPSR1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130123-A1 | 2-Phenyl-2h-pyridazine-3-ones | BASF AKTIENGESELLSCHAFT (DE) | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130123-A1 | 2-Phenyl-2h-pyridazine-3-ones | CNPY2, CBR3, CBR1 | NOTUM 936/4885SMN1; SMN2 4776/4885NPSR1 893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.