Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013961 | 1.00 | NPC1 (0.37) | NPC1RAB9APAX8NOTUMNPBWR1 | |
| SCHEMBL7017303 | 0.93 | NPC1 (0.37) | NPC1RAB9APAX8NOTUMNPBWR1 | |
| SCHEMBL7092396 | 0.93 | NPC1 (0.37) | NPC1RAB9APAX8NOTUMNPBWR1 | |
| SCHEMBL7092603 | 0.89 | NPBWR1 (0.38) | NPC1RAB9APAX8NOTUMNPBWR1 | |
| SCHEMBL7023491 | 0.89 | NPBWR1 (0.38) | NPC1RAB9APAX8NOTUMNPBWR1 | |
| SCHEMBL7018209 | 0.88 | ALDH1A1 (0.38) | NPC1RAB9APAX8NOTUMNPBWR1 | |
| SCHEMBL7093687 | 0.88 | ALDH1A1 (0.38) | NPC1RAB9APAX8NOTUMNPBWR1 | |
| SCHEMBL7089043 | 0.87 | NOTUM (0.40) | NPC1RAB9APAX8NOTUMNPBWR1 | |
| SCHEMBL7089040 | 0.87 | NOTUM (0.40) | NPC1RAB9APAX8NOTUMNPBWR1 | |
| SCHEMBL7018601 | 0.84 | NPC1 (0.34) | NPC1RAB9APAX8NOTUMNPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130123-A1 | 2-Phenyl-2h-pyridazine-3-ones | BASF AKTIENGESELLSCHAFT (DE) | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130123-A1 | 2-Phenyl-2h-pyridazine-3-ones | CNPY2, CBR3, CBR1 | NPC1 3803/4885RAB9A 3701/4885PAX8 2573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.