SCHEMBL7089255

SCHEMBL7089255

CCCc1ccnc(C=O)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 2/20 0.36
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
LMNA P02545 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HTR1D P28221 1/20 0.33
THRB P10828 1/20 0.33
NR3C2 P08235 2/20 0.32
KDM5A P29375 1/20 0.32
KDM5B Q9UGL1 1/20 0.32
CHRM2 P08172 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7092679 0.89 SKP2 (0.39) LMNAKDM4ECYP3A4TSHRMEN1
SCHEMBL6642166 0.85 NOS3 (0.52) NOS2NOS3NOS1LMNAKDM4E
SCHEMBL8830210 0.83 NOS2 (0.37) NOS2NOS3NOS1CNR1CNR2
SCHEMBL20920751 0.81 BTK (0.36) NOS2NOS3NOS1CNR1CNR2
SCHEMBL23909417 0.80 NR3C2 (0.49) KDM4EHTTNR3C2KDM5AKDM5B
SCHEMBL12826953 0.78 CCR1 (0.44) NOS2NOS3NOS1CNR1CNR2
SCHEMBL21645886 0.77 CDK1 (0.40) KDM4ENR3C2PDE3BPDE3ACA2
SCHEMBL6640410 0.77 HRH3 (0.40) KDM4EMEN1ALDH1A1HTTKMT2A
SCHEMBL15724953 0.77 CDK5 (0.32)
SCHEMBL764017 0.77 RECQL (0.52) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003084662-A2 COVALENTLY FIXED LIGAND SYSTEMS, NON-METALLOCENE SYSTEMS AND CATALYST SYSTEMS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF FOR POLYMERIZING OLEFINS CELANESE VENTURES GMBH (DE) 2003-10-16 WO disclosed