Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 2/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29935916 | 1.00 | RECQL (0.52) | RECQLPLAUKRASPRKCIGABRP | |
| SCHEMBL21645886 | 0.80 | CDK1 (0.40) | RECQL | |
| SCHEMBL28000578 | 0.80 | LOXL2 (0.34) | RECQLGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9899588 | 0.80 | RECQL (0.52) | RECQLPLAUKRASPRKCIGABRP | |
| SCHEMBL29026954 | 0.80 | LOXL2 (0.52) | LOXL2 | |
| SCHEMBL6642166 | 0.80 | NOS3 (0.52) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL21597037 | 0.78 | GABRP (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7089255 | 0.77 | NOS2 (0.36) | TSHRALDH1A1 | |
| SCHEMBL29393772 | 0.76 | RECQL (0.61) | RECQLPLAUKRASPRKCIMAOA | |
| SCHEMBL1411265 | 0.76 | RECQL (0.61) | RECQLPLAUKRASPRKCIMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164459-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2021-07-23 | — | — | CN | disclosed |
| EP-2431365-A1 | AZETIDINE COMPOUND AND MEDICINAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-6703373-B1 | ANTICARCINOGENIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-09 | — | — | US | disclosed |