SCHEMBL7900595

SCHEMBL7900595

CCOC(=O)C(Cl)=Cc1cc([N+](=O)[O-])ccc1Cl

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 1/20 0.49
MAPT P10636 5/20 0.49
ALDH1A1 P00352 3/20 0.49
KMT2A Q03164 3/20 0.49
KDM4E B2RXH2 2/20 0.47
LMNA P02545 2/20 0.47
NPSR1 Q6W5P4 1/20 0.46
POLB P06746 2/20 0.46
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HSD17B10 Q99714 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
FBP1 P09467 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7900591 1.00 GLO1 (0.49) GLO1MAPTALDH1A1KMT2AKDM4E
SCHEMBL11778862 0.88 GLO1 (0.59) GLO1MAPTALDH1A1KMT2AKDM4E
SCHEMBL7913985 0.85 MAPT (0.52) MAPTALDH1A1KMT2ALMNANPSR1
SCHEMBL7913986 0.85 MAPT (0.52) MAPTALDH1A1KMT2ALMNANPSR1
SCHEMBL10377329 0.85 GLO1 (0.65) GLO1MAPTALDH1A1KMT2AKDM4E
SCHEMBL10377330 0.85 GLO1 (0.65) GLO1MAPTALDH1A1KMT2AKDM4E
SCHEMBL9551005 0.83 ALDH1A1 (0.67) MAPTALDH1A1KMT2AKDM4ELMNA
SCHEMBL9551001 0.83 ALDH1A1 (0.67) MAPTALDH1A1KMT2AKDM4ELMNA
SCHEMBL7900516 0.81 FBP1 (0.53) GLO1MAPTALDH1A1KMT2AKDM4E
SCHEMBL7900517 0.81 FBP1 (0.53) GLO1MAPTALDH1A1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6211397-B1 CHLORINATION OF PHOSPHORANES BASF AKTIENGESELLSCHAFT (DE) 2001-04-03 US disclosed
US-6011181-A REDUCING THE LEVEL OF TRI-SUBSTITUTED PHOSPHINE, ARSINE AND/OR STIBINE OXIDE FROM A MIXTURE COMPRISING THE ADDITION OF A METAL SALT TO THE MIXTURE TO FORM A COMPLEX WITH THE OXIDE, AND REMOVING THE COMPLEX BASF AKTIENGESELLSCHAFT (DE) 2000-01-04 US disclosed
EP-0850902-A1 Process for reducing the level of trisubstituted phosphine, arsine and/or stibine oxide in a mixture BASF AKTIENGESELLSCHAFT (DE) 1998-07-01 EP disclosed
US-5569774-A Process for the preparation of chlorine-substituted olefins BASF AKTIENGESELLSCHAFT (DE) 1996-10-29 US disclosed
US-5324843-A Process for making 3,4,5,6-tetrahydrophthalimide derivatives BASF AKTIENGESELLSCHAFT (DE) 1994-06-28 US disclosed