Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089774 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAHTTALDH1A1MEN1 | |
| SCHEMBL7089449 | 0.82 | HDAC3 (0.48) | — | |
| SCHEMBL7089006 | 0.79 | HDAC3 (0.45) | — | |
| SCHEMBL7092254 | 0.78 | HDAC3 (0.44) | — | |
| SCHEMBL7088855 | 0.78 | CA12 (0.40) | — | |
| SCHEMBL6658567 | 0.77 | CA1 (0.45) | SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL7092305 | 0.76 | FOXO1 (0.46) | ALDH1A1 | |
| SCHEMBL7088914 | 0.76 | HSD17B10 (0.43) | LMNA | |
| SCHEMBL6659321 | 0.76 | HDAC3 (0.45) | — | |
| SCHEMBL6659312 | 0.76 | HDAC3 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003087127-A2 | ANTIMICROBIAL COMPOUNDS AGAINST STAPHYLOCOCCI, MYCOBACTERIA, AND OTHER INFECTIOUS AGENTS | EXEGENICS INC. (US) | 2003-10-23 | — | — | WO | claimed |