Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089782 | 0.87 | LMNA (0.43) | MAPTLMNAL3MBTL1SLC6A9SMN1; SMN2 | |
| SCHEMBL6856708 | 0.79 | MAPT (0.39) | MAPTLMNAL3MBTL1SLC6A9SMN1; SMN2 | |
| SCHEMBL29510827 | 0.76 | S1PR5 (0.56) | MAPTLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1462187 | 0.76 | S1PR5 (0.56) | MAPTLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL584781 | 0.74 | SLC2A1 (0.56) | MAPTSMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL30280404 | 0.74 | SLC2A1 (0.56) | MAPTSMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL3168485 | 0.73 | CYP4F2 (0.51) | MAPTL3MBTL1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6852995 | 0.72 | KEAP1 (0.47) | MAPTLMNAL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL6216285 | 0.72 | ELANE (0.53) | MAPTLMNAL3MBTL1HPGDHTT | |
| SCHEMBL31535966 | 0.72 | ALDH1A1 (0.45) | MAPTLMNAL3MBTL1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105078-A1 | Diphenyl derivatives | BAYER AKTIENGESSELLSCHAFT (DE) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105078-A1 | Diphenyl derivatives | DPP4, DPP3, DPM1 | MAPT 1592/4885LMNA 1567/4885L3MBTL1 3906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.