Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL709345 | 0.94 | ALOX5 (0.35) | CYP2C19POLBBLMATMALOX5 | |
| SCHEMBL14856825 | 0.92 | CYP2C19 (0.30) | CYP2C19 | |
| SCHEMBL14856877 | 0.87 | ALOX5 (0.31) | ALOX5 | |
| SCHEMBL709973 | 0.86 | CYP2C19 (0.34) | CYP2C19POLBBLMATM | |
| SCHEMBL712765 | 0.86 | CYP2C19 (0.34) | CYP2C19POLBBLMATM | |
| SCHEMBL711396 | 0.86 | CYP2C19 (0.34) | CYP2C19POLBBLMATM | |
| SCHEMBL13370527 | 0.80 | CYP2C19 (0.30) | CYP2C19 | |
| SCHEMBL3761489 | 0.79 | CYP2C19 (0.32) | CYP2C19POLBBLMATM | |
| SCHEMBL14856846 | 0.79 | CYP2C19 (0.32) | CYP2C19POLBBLMATM | |
| SCHEMBL14856880 | 0.79 | CYP2C19 (0.32) | CYP2C19POLBBLMATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342274-B1 | SULFUR-CONTAINING CYCLOALI PHATIC COMPOUND, FILLED SULFUR-VULCANIZABLE ELASTOMER COMPOSITION CONTAINING SULFUR-CONTAINING CYCLOALIPHATIC COMPOUND AND ARTICLES FABRICATED THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2013-04-17 | — | — | EP | claimed |
| US-8124206-B2 | Sulfur-containing cycloaliphatic compound, filled sulfur-vulcanizable elastomer composition containing sulfur-containing cycloaliphatic compound and articles fabricated therefrom | MOMENTIVE PERFORMANCE MATERIALS, INC. (US) | 2012-02-28 | — | — | US | claimed |
| EP-2342274-A1 | SULFUR-CONTAINING CYCLOALI PHATIC COMPOUND, FILLED SULFUR-VULCANIZABLE ELASTOMER COMPOSITION CONTAINING SULFUR-CONTAINING CYCLOALIPHATIC COMPOUND AND ARTICLES FABRICATED THEREFROM | Momentive Performance Materials Inc. (US) | 2011-07-13 | — | — | EP | claimed |
| WO-2010059402-A1 | SULFUR-CONTAINING CYCLOALI PHATIC COMPOUND, FILLED SULFUR-VULCANIZABLE ELASTOMER COMPOSITION CONTAINING SULFUR-CONTAINING CYCLOALIPHATIC COMPOUND AND ARTICLES FABRICATED THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2010-05-27 | — | — | WO | claimed |
| US-20100112259-A1 | Sulfur-containing cycloaliphatic compound, filled sulfur-vulcanizable elastomer composition containing sulfur-containing cycloaliphatic compound and articles fabricated therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. | 2010-05-06 | — | — | US | claimed |
| US-8846170-B2 | Sulfur-containing cycloaliphatic compound, filled sulfur-vulcanizable elastomer composition containing sulfur-containing cycloaliphatic compound and articles fabricated therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2014-09-30 | — | — | US | disclosed |
| EP-2342274-B1 | SULFUR-CONTAINING CYCLOALI PHATIC COMPOUND, FILLED SULFUR-VULCANIZABLE ELASTOMER COMPOSITION CONTAINING SULFUR-CONTAINING CYCLOALIPHATIC COMPOUND AND ARTICLES FABRICATED THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2013-04-17 | — | — | EP | disclosed |
| US-20120116002-A1 | SULFUR-CONTAINING CYCLOALIPHATIC COMPOUND, FILLED SULFUR-VULCANIZABLE ELASTOMER COMPOSITION CONTAINING SULFUR-CONTAINING CYCLOALIPHATIC COMPOUND AND ARTICLES FABRICATED THEREFROM | MOMENTIVE PERFORMANCE MATERICALS INC. (US) | 2012-05-10 | — | — | US | disclosed |
| US-8124206-B2 | Sulfur-containing cycloaliphatic compound, filled sulfur-vulcanizable elastomer composition containing sulfur-containing cycloaliphatic compound and articles fabricated therefrom | MOMENTIVE PERFORMANCE MATERIALS, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| EP-2342274-A1 | SULFUR-CONTAINING CYCLOALI PHATIC COMPOUND, FILLED SULFUR-VULCANIZABLE ELASTOMER COMPOSITION CONTAINING SULFUR-CONTAINING CYCLOALIPHATIC COMPOUND AND ARTICLES FABRICATED THEREFROM | Momentive Performance Materials Inc. (US) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010059402-A1 | SULFUR-CONTAINING CYCLOALI PHATIC COMPOUND, FILLED SULFUR-VULCANIZABLE ELASTOMER COMPOSITION CONTAINING SULFUR-CONTAINING CYCLOALIPHATIC COMPOUND AND ARTICLES FABRICATED THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2010-05-27 | — | — | WO | disclosed |
| US-20100112259-A1 | Sulfur-containing cycloaliphatic compound, filled sulfur-vulcanizable elastomer composition containing sulfur-containing cycloaliphatic compound and articles fabricated therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100112259-A1 | Sulfur-containing cycloaliphatic compound, filled sulfur-vulcanizable elastomer composition containing sulfur-containing cycloaliphatic compound and articles fabricated therefrom | CRHR2, CRH, CRHR1 | CYP2C19 2379/4885POLB 2531/4885BLM 1699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.