Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5485052 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2ATSHRALOX15 | |
| SCHEMBL29177446 | 0.77 | MEN1 (0.35) | SMN1; SMN2MEN1KMT2APIK3CD | |
| SCHEMBL10046126 | 0.76 | DRD2 (0.47) | PIK3CDCA2CA5A | |
| SCHEMBL29177401 | 0.76 | PIK3CD (0.42) | SMN1; SMN2KMT2APIK3CDKIF11FFAR4 | |
| SCHEMBL29010952 | 0.75 | CA12 (0.53) | MEN1KMT2ATSHRCA2NPC1 | |
| SCHEMBL29177251 | 0.75 | MEN1 (0.47) | SMN1; SMN2MEN1KMT2ATSHRCA2 | |
| SCHEMBL24159171 | 0.75 | TSHR (0.47) | SMN1; SMN2MEN1KMT2ATSHRHSD17B10 | |
| SCHEMBL16473528 | 0.72 | PARP10 (0.39) | SMN1; SMN2MEN1KMT2ATSHRHSD17B10 | |
| SCHEMBL5286604 | 0.71 | ALDH1A1 (0.59) | MEN1KMT2ACA2ALDH1A1MAPT | |
| SCHEMBL30539307 | 0.71 | ALDH1A1 (0.59) | MEN1KMT2ACA2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337530-A1 | OXAZOLIDINONES HAVING A BENZANNULATED 6-OR 7-MEMBERED HETEROCYCLE AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002059115-A1 | OXAZOLIDINONES HAVING A BENZANNULATED 6-OR 7-MEMBERED HETEROCYCLE AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |