Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088585 | 0.89 | MEN1 (0.53) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7319925 | 0.83 | KDM4E (0.61) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7093037 | 0.80 | MAPT (0.49) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7673685 | 0.77 | MEN1 (0.56) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6673404 | 0.72 | MEN1 (0.50) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL20105594 | 0.71 | KDM4E (0.64) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9300858 | 0.71 | KDM4E (0.72) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6350010 | 0.71 | ALDH1A1 (1.00) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8577820 | 0.70 | HTT (0.43) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7674391 | 0.70 | MEN1 (0.47) | KDM4EMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799040-B1 | TRISUBSTITUTED THIOXANTHINES | EURO CELTIQUE SA (LU) | 2003-08-20 | — | — | EP | disclosed |
| US-6268373-B1 | ENZYME INHIBITORS | EURO-CELTIQUE S.A. (LU) | 2001-07-31 | — | — | US | disclosed |
| US-6025361-A | EFFECTIVE PDE IV INHIBITORS, ASTHMA | EURO-CELTIQUE, S.A. (LU) | 2000-02-15 | — | — | US | disclosed |
| US-5977119-A | Trisubstituted thioxanthines | EURO-CELTIQUE, S.A. (LU) | 1999-11-02 | — | — | US | disclosed |
| EP-0799040-A4 | TRISUBSTITUTED THIOXANTHINES | EURO CELTIQUE SA (LU) | 1998-04-01 | — | — | EP | disclosed |
| EP-0799040-A1 | TRISUBSTITUTED THIOXANTHINES | Euroceltique S.A. (LU) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996018400-A1 | TRISUBSTITUTED THIOXANTHINES | EURO-CELTIQUE, S.A. (LU) | 1996-06-20 | — | — | WO | disclosed |