Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096394 | 0.82 | PTGS2 (0.57) | CYP11B2CYP11B1CYP19A1PTGS2ALDH1A1 | |
| SCHEMBL30487693 | 0.82 | PTGS2 (0.57) | CYP11B2CYP11B1CYP19A1PTGS2ALDH1A1 | |
| SCHEMBL2626997 | 0.79 | CYP11B1 (0.33) | CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL7094272 | 0.75 | ABCG2 (0.40) | CYP11B2CYP11B1NPC1RAB9AKDM4E | |
| SCHEMBL6940332 | 0.74 | CYP11B1 (0.35) | CYP11B2CYP11B1CYP19A1NPC1KDM4E | |
| SCHEMBL21776765 | 0.73 | PTGS2 (0.41) | CYP11B2CYP11B1CYP19A1NPC1RAB9A | |
| SCHEMBL26746931 | 0.73 | CYP11B1 (0.32) | CYP11B2CYP11B1CYP19A1NPC1RAB9A | |
| SCHEMBL8972556 | 0.72 | PTGS2 (0.56) | CYP11B2CYP11B1CYP19A1NPC1RAB9A | |
| SCHEMBL15702648 | 0.72 | L3MBTL1 (0.35) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29127912 | 0.71 | PTGS2 (0.55) | CYP11B2CYP11B1CYP19A1PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910560-B1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-6271411-B1 | REACTING AN INDENE WITH AN ARENE COMPOUND SUBSTITUTED WITH AN HALOGEN ATOM, PREFERABLY A IODINE ATOM, OR WITH AN ORGANOSULPHONATE GROUP, IN A BASIC MEDIUM IN THE PRESENCE OF A PALLADIUM CATALYST. | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-08-07 | — | — | US | disclosed |
| EP-0910560-A1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | Montell Technology Company bv (NL) | 1999-04-28 | — | — | EP | disclosed |
| WO-1998046547-A1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1998-10-22 | — | — | WO | disclosed |