Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | IDH2 | P48735 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16411529 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1HTTRECQLTP53 | |
| SCHEMBL5495442 | 0.76 | TP53 (0.46) | TP53POLBGAATDP1GPR142 | |
| SCHEMBL24865433 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HTTRECQLTP53POLB | |
| SCHEMBL24865212 | 0.73 | ALDH1A1 (0.46) | ALDH1A1HTTRECQLTDP1EGFR | |
| SCHEMBL24629506 | 0.73 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1HTTRECQLTDP1 | |
| SCHEMBL6512204 | 0.72 | AR (0.40) | USP2SMN1; SMN2ALDH1A1HTTRECQL | |
| SCHEMBL1921482 | 0.72 | KIF11 (0.70) | KIF11SMN1; SMN2ALDH1A1TP53GAA | |
| SCHEMBL24865750 | 0.72 | HTT (0.46) | SMN1; SMN2ALDH1A1HTTRECQLTP53 | |
| SCHEMBL30336849 | 0.72 | HTT (0.46) | SMN1; SMN2ALDH1A1HTTRECQLTP53 | |
| SCHEMBL394991 | 0.72 | KIF11 (0.70) | KIF11SMN1; SMN2ALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363897-A2 | ANTAGONISTS OF MCP-1 FUNCTION AND METHODS OF USE THEREOF | TELIK, INC. (US) | 2003-11-26 | — | — | EP | claimed |
| WO-2002070509-A2 | ANTAGONISTS OF MCP-1 FUNCTION AND METHODS OF USE THEREOF | TELIK, INC. (US) | 2002-09-12 | — | — | WO | claimed |