Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30666622 | 1.00 | CYP11B1 (0.53) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 | |
| SCHEMBL10402898 | 0.85 | CYP11B1 (0.56) | CYP11B1CYP11B2PTGS2CYP1A2CYP19A1 | |
| SCHEMBL8058170 | 0.84 | CYP11B2 (0.61) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 | |
| SCHEMBL6285180 | 0.84 | CYP11B2 (0.61) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 | |
| SCHEMBL31608568 | 0.84 | CYP11B2 (0.65) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 | |
| SCHEMBL319265 | 0.84 | CYP11B2 (0.65) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 | |
| SCHEMBL30666795 | 0.83 | CYP11B2 (0.51) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 | |
| SCHEMBL30487694 | 0.82 | CYP11B1 (0.54) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 | |
| SCHEMBL6287169 | 0.82 | CYP11B1 (0.54) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 | |
| SCHEMBL31666281 | 0.82 | CYP11B2 (0.62) | CYP11B1CYP11B2PTGS2IP6K1IP6K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910560-B1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-6271411-B1 | REACTING AN INDENE WITH AN ARENE COMPOUND SUBSTITUTED WITH AN HALOGEN ATOM, PREFERABLY A IODINE ATOM, OR WITH AN ORGANOSULPHONATE GROUP, IN A BASIC MEDIUM IN THE PRESENCE OF A PALLADIUM CATALYST. | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-08-07 | — | — | US | disclosed |
| CN-1228072-A | Process for preparing 2-aryl-substituted indenes | MONTELL TECHNOLOGY COMPANY BV (NL) | 1999-09-08 | — | — | CN | disclosed |
| EP-0910560-A1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | Montell Technology Company bv (NL) | 1999-04-28 | — | — | EP | disclosed |
| WO-1998046547-A1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1998-10-22 | — | — | WO | disclosed |